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Biomedical subjects

Catriona Ooi

Publications and source records attributed to Catriona Ooi.

8 recordsLinked to original sources

Syphilis treatment: old and new.

Syphilis has challenged scientists and clinicians since its first appearance in the late 1400s and debate continues to surround the best practice in management. Difficulties in defining the goals of successful treatment have contributed to problems in determining recommendations for the ideal management. Treatment regimens currently in use were developed before randomised controlled trials became standard. This, combined with national differences in disease definition, staging and varying interpretations of the studies, as well as the emergence of complicating comorbid conditions, such as HIV, has resulted in a lack of consensus for treatment. This paper will discuss the history and current treatment of syphilis focusing on dilemmas faced by clinicians today, including the emergence of a resistant strain. Despite the difference between current national guidelines, penicillin G largely remains the treatment of choice. Close follow up, monitoring and ensuring adequate compliance remain the most important aspects in the treatment of syphilis.

Anti-Bacterial Agents↗

STIs in pregnancy. An update for GPs.

BACKGROUND: Pregnancy and sexually transmitted infections (STIs) are both consequences of unprotected vaginal sex. In addition to causing maternal morbidity in their own right, many STIs including human immunodeficiency virus (HIV) can be transmitted to the neonate. Antenatal screening during pregnancy provides an opportunity to minimise or eliminate the antepartum, intrapartum and postpartum consequences of most STIs. OBJECTIVE: This article discusses the diagnosis, management and treatments available for STIs in pregnancy to minimise morbidity and mortality for both mother and child. DISCUSSION: HIV testing in antenatal care should be added to routine syphilis and hepatitis B serology, as effective HIV interventions can significantly reduce the risk of mother-child transmission. Consideration should be given to testing in women less than 25 years of age for chlamydia and those women at increased sexual risk. Male partners should not be forgotten and contact tracing, treatment and follow up offered. Due to the very small risk associated with genital warts and genital herpes, normalisation, information and reassurance are appropriate for the majority of women affected.

Adolescent↗

The sexually transmitted infection 'check up'.

BACKGROUND: Many sexually transmitted infections (STIs) and blood borne viruses (BBV) such as HIV are asymptomatic. Early detection is important for minimising associated risks. With appropriate treatment and management (including contact tracing) it is possible to substantially reduce morbidity as well as transmission to sexual partners and the neonate. OBJECTIVE: This paper outlines which tests should be administered to otherwise 'well' individuals. It also examines the questions of when, why and how to respond to requests for an STI 'screen' or 'check up'. DISCUSSION: Testing and screening for asymptomatic STIs and BBV are important, especially in situations where proven interventions can decrease morbidity and transmission. Screening for STIs also provides the opportunity in a one-on-one consultation for health promotion. Sexually transmitted infection testing can also initiate a conversation about 'safer sex' and may help address other concerns patients may have.

Humans↗

Pelvic inflammatory disease.

BACKGROUND: Pelvic inflammatory disease (PID) is a treatable condition with serious long term sequelae. Due to the wide spectrum of disease and clinical presentation, diagnosis can often be challenging. OBJECTIVE: This article discusses the diagnosis, management and treatment of PID in the general practice setting. DISCUSSION: Prompt and effective treatment is essential in cases of PID. A high index of suspicion for symptomatic women at risk may help decrease the burden of serious associated morbidity.

Female↗

Syphilis. Diagnosis and management in general practice.

BACKGROUND: Although largely regarded as an uncommon condition, recent outbreaks of syphilis in Western nations combined with the increasing popularity of travel are likely to result in increases in rates in Australia. OBJECTIVES: To discuss the common modes of presentation and interpretation of syphilis tests, and the treatment of syphilis at various stages. DISCUSSION: Accurate interpretation of syphilis test results is essential for staging of disease and appropriate treatment. With these skills many cases of syphilis can be effectively managed in a general practice setting.

Australia↗

Genital herpes. An approach for general practitioners in Australia.

BACKGROUND: Genital herpes is a common sexually transmitted infection that is most often asymptomatic and remains largely undiagnosed. OBJECTIVE: To discuss the diagnosis, management and treatments available for genital herpes infections. DISCUSSION: Genital herpes is a common infection with significant associated morbidity. Along with diagnosis and appropriate treatment, patient education, counselling and support are essential for effective management.

Adolescent↗