Inhalation of chemical and particulate products of smoke is one of the principal determinant of mortality following burn injury. Inflammatory responses have been implicated in the pathogenesis of lung injury after smoke inhalation. In the current study, we tested the inhibitory effect of Fucoidin on the neutrophil rolling stage of inflammatory response and determined the degree of pulmonary injury. Fifteen rats were divided into three groups: sham group (N: 5) of rats inhaled room air; control group (N: 5) inhaled smoke, and experimental group inhaled smoke and received Fucoidin. All the rats were sacrificed 24h after smoke inhalation. The trachea and lungs were removed totally; samples for histopathological and biochemical (myeloperoxidase (MPO)) analysis were taken from each lung and trachea. Morphologic studies using light and electron microscopes showed a decrease in lung parenchymal and tracheoepithelial injury in the experiment group of rats. Also, biochemical analysis of tissue MPO was significantly lower in test group than in control group. These results suggest that the inhibition of neutrophil rolling leads to a reduction of neutrophil invasion to pulmonary parenchyma and trachea, which may be beneficial for attenuating neutrophil mediated inhalation injury.

Analysis of Variance↗

PubMed2003

Lyophilised polyurethane membrane dressing for surgically-separated pseudosyndactyly in epidermolysis bullosa.

The results of paraffin gauze dressing and lyophilised polyurethane membrane dressing were studied in a patient with surgically-separated pseudosyndactyly of dystrophic epidermolysis bullosa. Polyurethane membrane dressing decreased the time to epithelialisation and the need for anaesthesia.

Bandages↗

PubMed2003

Surgical glove cover for intraoperative flap design.

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Gloves, Surgical↗

PubMed2002

Neurotization of the frontal muscle after scalp replantation: case report.

A case of immediate replantation of an avulsed scalp by microvascular anastomosis is presented. Microvascular replantation of the scalp seems to offer significant social and psychological advantages over secondary reconstructive procedures. The significance of the case presented is the regaining of the motor neural function of the facial nerve after 38 months.

Adult↗