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Chang-En Pu

Publications and source records attributed to Chang-En Pu.

3 recordsLinked to original sources

Population data on the X chromosome short tandem repeat loci DXS10011, DXS101, DXS6789, DXS7132, DXS8377, and DXS9895 in Taiwan.

X chromosome linked short tandem repeat (STR) are powerful auxiliary systems to genomic STR, they are helpful for differentiating if two women have the same father directly, avoiding some of the ambiguity generated from sibship estimation. This report contains the results of population studies on the X chromosome STR DXS10011, DXS101, DXS6789, DXS7132, DXS8377 and DXS9895 carried out in Taiwan. The common alleles of each locus were sequenced and used in a control ladder to type unknown samples. The numbers of unrelated individuals were 273 (female 92 and male 181) for DXS10011 locus, 448 (female 135 and male 313) for DXS101 locus, 447 (female 135 and male 312) for DXS6789 locus, 414 (female 119 and male 295) for DXS7132 locus, 450 (female 135 and male 315) for DXS8377 locus and 413 (female 120 and male 293) for DXS9895 locus. These STR polymorphisms will be a useful marker for parentage testing especially when disputed blood relative is female.

Chromosomes, Human, X↗

Asian online Y-STR Haplotype Reference Database.

For several years Y-chromosomal microsatellites (short tandem repeats, STRs) have been well established in forensic practice. In this context, the genetic characteristics of the Y chromosome (i.e. its paternal inheritance and lack of recombination) render STRs particularly powerful. However, genetic differences between male populations appear to be larger for Y-STRs than for autosomal STRs, a fact that is most likely due to the higher sensitivity of Y-chromosomal lineages to genetic drift (Forensic Sci Int 118 (2001) 153). The assessment of probabilities for matches between haplotyped male persons or traces/persons requires the typing of a large number of haplotypes in the appropriate reference populations. The haplotype data of a large number of European as well as South and North American populations have been collected and are continuously published online (Y-STR Haplotype Reference Database--YHRD; http://www.ystr.org). The most recent multicentric effort has led to the establishment of an Asian YHRD (http://www.ystr.org/asia) which has been available since January 2002. All databases are maintained and curated at the Institute of Legal Medicine, Humboldt-University, Berlin and will soon be fused to a global repository including populations from all continents.

Asia↗