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Biomedical subjects

Charles H. Kellner

Publications and source records attributed to Charles H. Kellner.

10 recordsLinked to original sources
PubMed1993

Combined ECT and Antidepressant Drug Therapy.

The current literature on the interaction between antidepressant drugs and electroconvulsive therapy (ECT) is reviewed. Tricyclic antidepressants, atypical antidepressants, and monoamine oxidase inhibitors are discussed. The efficacy of combinations and possible adverse effects (mainly cardiovascular and seizure threshold effects) are considered. Many previous studies on the efficacy of combinations used inadequate methods, and the safety data consist largely of anecdotes and small case series. Additional studies are needed to assess the safety and efficacy of the combined use of antidepressants and ECT.

Journal Article↗
PubMed1992

Weekly ECT in Geriatric Depression.

Fifteen elderly depressed psychiatric inpatients were randomly assigned to receive either standard three-times-weekly electroconvulsive therapy (ECT) or once-weekly ECT. Outcome measures included cognitive assessment and antidepressant response. Although both groups improved with treatment, the three-times-weekly group improved substantially more quickly. There was no difference in cognitive effect between the two groups. We conclude that the traditional three-times-weekly schedule of ECT may optimally balance speed of antidepressant response and cognitive impairment.

Journal Article↗
PubMed1991

ECT in the Presence of Severe Cervical Spine Disease.

We present a case of the safe administration of electroconvulsive therapy (ECT) to a depressed patient with severe, unstable cervical spine disease. Using adequate muscle relaxation, a course of ECT treatments was given with excellent results. Although fears about the use of ECT in the presence of spine disease persist, attention to modern ECT technique allows a safe treatment course.

Journal Article↗
PubMed1991

Normalization of Augmented TRH Stimulation Test in Response to ECT.

A 78-year-old woman with a major depression and subclinical hypothyroidism was successfully treated with ECT. Her abnormally augmented pretreatment thyrotropin-releasing hormone (TRH) stimulation test normalized. We discuss the interaction of electroconvulsive therapy (ECT) and the thyroid axis.

Journal Article↗