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Chen-Nen Chang

Publications and source records attributed to Chen-Nen Chang.

20 records · Page 2Linked to original sources

Minimally invasive procedure for ventriculoatrial shunt-combining a percutaneous approach with real-time transesophageal echocardiogram monitoring: report of six cases.

To make the ventriculo atrial (VA) shunt procedure less invasive and avoid atrial catheter malpositioning, we combined a percutaneous approach with transesophageal echocardiogram (TEE) to monitor the atrial catheter tip. From July 1995 to October 1996, we performed 6 VA shunt procedures by combining these 2 techniques. Except for one patient who had a concomitant Port-A catheter, which obscured the detection of TEE in the procedure, all other atrial catheters achieved ideal positioning and good function. The mean operation time was shorter, and the complications were fewer than those using the conventional procedure in our hospital. In addition to this particular aspect, by combining these 2 techniques, the VA shunt procedure can be performed much less invasively, but more accurately, quickly, and safely.

Adult↗

Homocysteine, vitamin B(6), and lipid in cardiovascular disease.

OBJECTIVES: Elevated homocysteine (Hcy) is considered an independent risk factor for cardiovascular disease (CVD). An elevated plasma Hcy level may interact with conventional CVD risk factors to further increase vascular disease risk. Therefore, we investigated the plasma levels of Hcy, vitamin B(6) status (pyridoxal phosphate and pyridoxal), and lipid profile in patients with CVD. METHODS: Possible associations between sex, age, body mass index (BMI), and waist-to-hip ratio (WHR) to levels of plasma Hcy and plasma Hcy to vitamin B(6) status and lipid profile were examined. RESULTS: Plasma Hcy level, body mass index, and waist-to-hip ratio were significantly higher in patients with CVD than in controls. Male CVD patients had significantly higher plasma Hcy levels than did female patients. Plasma levels of pyridoxal phosphate and total B(6) aldehyde were significantly higher in male than in female patients. Plasma Hcy levels of patients did not correlate to their plasma vitamin B(6) status or to their lipid profiles. Plasma Hcy level correlated positively with age, body mass index, and waist-to-hip ratio (P < 0.0001). CONCLUSIONS: This suggested that patients with CVD have higher levels of plasma Hcy that are influenced by sex, age, body mass index, and waist-to-hip ratio and not by their plasma vitamin B(6) status and lipid profiles.

Adult↗