Appropriateness of methadone maintenance treatment--from individual practice to evidence-based medicine.
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Evidence-Based Medicine↗
Biomedical subjects
Christian Haasen
Publications and source records attributed to Christian Haasen.
Comorbidity of schizophrenia and galactosemia: effective clozapine treatment with weight gain.
Weight gain with atypical antipsychotics such as clozapine has been hypothesized to have a multifactorial genesis. Beside changes in neurotransmitter systems caused by antipsychotic-induced receptor blockade, hormonal changes and other neuroleptic side-effects (sedation, reduced activity, reduced basal metabolic rate, dry mouth) are also discussed. Our unique case report of a patient with comorbid galactosemia and schizophrenia is an interesting example of weight gain being a positive side-effect of clozapine, not necessarily associated with increased appetite and higher caloric intake.
Adult↗
Alcohol consumption in Alzheimer's disease. A case report.
As late-onset alcohol consumption is rare, it often indicates a different underlying disorder. We present a case where late-onset alcohol drinking occurred during the onset of Alzheimer's disease.
Aged↗
Treatment of drug addiction in traumatised refugees. A case report.
The comorbidity of post-traumatic stress disorder (PTSD) and drug addiction is quite often overlooked in refugees. However, the simultaneous treatment of both disorders is of elemental importance for a positive outcome in addicted and traumatised refugees. Furthermore, mutual misinterpretations of habits, behaviours and reactions through negligence of the distinct sociocultural context of patient and clinician often leads to unfavourable developments. These observations are exemplified in this case report.
Adult↗
Smoking cocarettes: a less harmful alternative of cocaine use?
Smoking cocaine hydrochloride in the form of cocarettes is a method of cocaine use that has not been described in the scientific literature so far. Nonetheless it seems to be a somewhat common method of cocaine use in order to avoid the nasal irritation. Three case reports are presented in order to discuss the possibility.
Adult↗
Effect of zotepine, olanzapine and risperidone on hostility in schizophrenic patients.
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Analysis of Variance↗
Switching to amisulpride due to hepatic complications.
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Adult↗
Belief systems as coping factors for traumatized refugees: a pilot study.
The severity of traumatization seems to correlate with a more severe course of post-traumatic stress disorder (PTSD) (and other post-traumatic disorders), while firm belief systems have been found to be a protective factor against post-traumatic disorders. This study sought to determine the role of belief systems in the outcome of psychotherapy for traumatized refugees. The charts of 141 consecutively treated refugees were evaluated retrospectively. A firm belief system was found to be an important predictor for a better therapy outcome. The importance of a firm belief system as a coping factor, which should be used as an instrument in therapy, is discussed.
Adaptation, Psychological↗
Executive functioning in obsessive-compulsive disorder, unipolar depression, and schizophrenia.
The present study investigated whether schizophrenic, unipolar depressive, and obsessive-compulsive psychiatric patients show a distinguishable profile in tasks considered sensitive to frontal lobe functioning. Three psychiatric samples, each comprising 25 patients with little symptomatic overlap, were compared to 70 healthy controls. Participants completed several executive tasks (Wisconsin Card Sorting Test (WCST), verbal fluency, digit span, Stroop, and Trail-Making). Except for age, which was entered as a covariate, subjects did not differ in any sociodemographic background variable. Healthy controls showed superior performance relative to depressive and schizophrenic patients who exhibited comparable deficits in all tasks. Obsessive-compulsive disorder (OCD) patients revealed dysfunctions in the Trail-Making Tests A and B and in the fluency task. Dysfunctions in the domains of working memory, verbal fluency, distractibility, and concept formation were not confined to a specific psychiatric population.
Journal Article↗