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Biomedical subjects

Christina Willeboer

Publications and source records attributed to Christina Willeboer.

2 recordsLinked to original sources

Comparing cochlear implant users' speech performance with processor fittings based on conventionally determined T and C levels or on compound action potential thresholds and live-voice speech in a prospective balanced crossover study.

OBJECTIVE: The objective of the present study is to improve the efficiency of the fitting procedure of cochlear implant processors by making use of measurements of the electrically evoked compound actio potential (ECAP) and live-voice speech. DESIGN: In a randomised prospective cross-over design we compare speech performance of eighteen adult subjects when following the conventional fitting procedure to a procedure in which we use the profile of the ECAP threshold levels across the full electrode array measured intra-operatively. The overall level of the profile is shifted (by an equal amount of current units per electrode) until we find the threshold for live speech (new T levels) and the loudness comfort level (new C levels). Each fitting procedure is tested for 6 wk. Speech performance is measured in quiet and in noise every other week. RESULTS: The results show little difference between the scores (Dutch CVC words) for the conventional fitting procedure and the ECAP based fitting, although the T and C levels may differ markedly. CONCLUSION: The new fitting procedure is much faster and easier in the initial phase. Further improvement of performance may be obtained in a later stage of the fitting procedure by changing some individual electrodes on the basis of subjective responses.

Action Potentials↗

Speech perception in nucleus CI24M cochlear implant users with processor settings based on electrically evoked compound action potential thresholds.

Adjusting the speech processor of a cochlear implant, per electrode, to the individual's response is a laborious task that may interfere with a user-friendly start of implant-mediated hearing, particularly in children. This research concerns the possibility of processor adjustment based on a profile derived from measurements of the electrically evoked compound action potential (ECAP) thresholds across the electrode array, followed by adjustment of the overall level of the profile to the hearing threshold and maximum comfortable loudness level using live voice. The results for CVC word lists show that speech perception is quite insensitive to the threshold setting of the speech processor. On average, the speech score does not decrease by more than 10% when, with the new method, the threshold setting comes out so much lower that the dynamic range has doubled. In contrast, the speech score appears to be sensitive to an increase of the maximum high-frequency stimulation settings for the basal electrodes, resulting in lower scores at these higher settings. The correlation between the overall ECAP thresholds and conventionally measured subjective thresholds is weak (r = 0.64). However, the correlation between the slopes of these threshold curves is satisfactory (r = 0.82). The correlation between the ECAP thresholds and the maximum stimulation levels is poor, both with respect to overall level and slope (r = 0.39 and 0.36, respectively). Applicability of the ECAP threshold in processor adjustment could not be demonstrated in this study. Prediction of the most critical factor in speech perception, the slope of the maximum stimulation curve, from the ECAP thresholds is poor. However, considering habituation to the initial processor setting of at least 6 months, the small decrease in the CVC scores with the new setting suggests that a more user-friendly adjustment procedure can be developed.

Acoustic Stimulation↗