Biomedical subjects

Christine M Muñoz

Publications and source records attributed to Christine M Muñoz.

3 recordsLinked to original sources

PubMed2006

Acral syringomas presenting as a photosensitive papular eruption.

A 43-year-old woman presented with a recurrent and remitting eruption of reddish-brown papules in the sun-exposed areas of the arms and forearms that had been present for 2 years. Results of a histopathologic examination revealed syringoma. To the best of our knowledge, this is the first case report of syringomas confined to sun-exposed areas with a recurrent and remitting course over time. We also review the literature on acral syringomas.

Adult↗

PubMed2004

Successful treatment of persistent melanoma in situ with 5% imiquimod cream.

BACKGROUND: Five percent imiquimod cream, a topically applied immune response modifier with potent antiviral and antitumor activity, has been reported to be effective in the management of lentigo maligna and cutaneous metastases from melanoma. OBJECTIVE: We report a case in which 5% imiquimod cream was effective in the management of a persistent melanoma in situ. METHODS: Five percent imiquimod cream was applied to the affected area twice to three times a week, as tolerated. RESULTS: After 4 months of treatment, repeated biopsies of the previously affected areas showed complete regression of the melanoma. CONCLUSION: Treatment of melanoma in situ of sun-damaged areas with 5% imiquimod cream certainly appears warranted in selected cases where surgical procedures have failed or are not feasible owing to factors such as size and/or localization of the lesion, advanced age, or deteriorated medical status of the patient. Rigorous posttreatment follow-up is mandatory, because long-term recurrence rates after treatment of melanoma in situ with imiquimod are yet unknown.

Administration, Cutaneous↗

PubMedDate not supplied

Granular parakeratosis.

This is a report of a 60 year-old black female patient presenting with pruritic brownish crusted plaques on both axillae of one month evolution. Histopathology revealed findings characteristic of axillary granular parakeratosis. This entity was first described by Northcutt et al in 1991. Since then, involvement of other intertriginous areas have also been reported. A review of the literature was performed and the term granular parakeratosis is suggested to emphasize its pathognomonic histopathologic features.

Female↗