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Biomedical subjects

Christo I Tchervenkov

Publications and source records attributed to Christo I Tchervenkov.

31 records · Page 2Linked to original sources
PubMed2003

Outcomes after the Norwood operation in neonates with critical aortic stenosis or aortic valve atresia.

OBJECTIVE: This study was undertaken to determine the demographic, anatomic, institutional, and surgical risk factors associated with outcomes after the Norwood operation. METHODS: A total of 710 of 985 neonates with critical aortic stenosis or atresia enrolled in a prospective 29-institution study between 1994 and 2000 underwent the Norwood operation. Admission echocardiograms were independently reviewed for 64% of neonates. Competing risks analyses were constructed for outcomes after Norwood operation and after cavopulmonary shunt. Incremental risk factors for outcome events were sought. RESULTS: Overall survivals after the Norwood operation were 72%, 60%, and 54% at 1 month, 1 year, and 5 years, respectively. According to competing risks analysis, 97% of neonates reached a subsequent transition state by 18 months after Norwood operation, consisting of death (37%), cavopulmonary shunt (58%), or other state (2%, cardiac transplantation, biventricular repair, or Fontan operation). Risk factors for death occurring before subsequent transition included patient-specific variables (lower birth weight, smaller ascending aorta, older age at Norwood operation), institutional variables (institutions enrolling < or =10 neonates, two institutions enrolling >/=40 neonates), and procedural variables (shunt originating from aorta, longer circulatory arrest time, and management of the ascending aorta). Of neonates undergoing cavopulmonary shunt, 91% had reached a subsequent transition state by 6 years after cavopulmonary shunt, consisting of Fontan operation (79%), death (9%), or cardiac transplantation (3%). Risk factors for death occurring before subsequent transition included younger age at cavopulmonary shunt and need for right atrioventricular valve repair. CONCLUSIONS: Competing risks analysis defines the prevalence of the various outcomes after Norwood operation and predicts improved outcomes with successful modification of controllable risk factors.

Aorta↗
PubMed2002

Congenital heart surgery nomenclature and database project. Update and proposed data harvest.

In 1998, the first report of the Society of Thoracic Surgery (STS) National Congenital Heart Surgery Database defined clinical features for 18 congenital heart disease categories, providing a significant amount of important information and pinpointing database strengths and weaknesses. Following this report, the STS Congenital Heart Surgery Committee, working with the European Association of Cardio-Thoracic Surgery and the European Congenital Heart Surgeons Foundation, initiated the International Congenital Heart Surgery and Nomenclature Database Project. To standardize nomenclature and reporting strategies and establish a foundation for an international congenital heart surgery database. The project's first report was published in the Annals of Thoracic Surgery in April 2000. The current report outlines modifications to the minimal dataset and diagnosis and procedure short lists.

Databases, Factual↗
PubMed2002

Single-stage anatomical repair of complete atrioventricular canal, double-outlet right ventricle, and cor triatriatum using ventricular septal defect translocation.

A 17-month-old girl underwent successful single-stage anatomic repair using a technique of ventricular septal defect translocation for complete atrioventricular canal, double-outlet right ventricle, pulmonary stenosis, cor triatriatum, and left superior vena cava to an unroofed coronary sinus. We describe the repair and present clinical and angiographic data from 9 years follow-up.

Cardiac Surgical Procedures↗
PubMed2002

Congenital Heart Surgery Nomenclature and Database Project: update and proposed data harvest.

The first report of The Society of Thoracic Surgeons (STS) National Congenital Heart Surgery Database in 1998 reported the clinical features of 18 congenital heart categories. The report provided a significant amount of important information and also highlighted the strengths and weaknesses of the existing database. Following this report the STS Congenital Heart Surgery Committee in cooperation with the European Association of Cardio-Thoracic Surgery and the European Congenital Heart Surgeons Foundation initiated the International Congenital Heart Surgery Nomenclature and Database Project. The goal was to begin the standardization of nomenclature reporting strategies and establish the foundations for an international congenital heart surgery database. The first report of the International Congenital Heart Surgery Nomenclature Project was published in The Annals of Thoracic Surgery in April 2000. The current report outlines modifications to the minimum dataset as well as the diagnoses and procedure short lists. Plans for the next STS National Congenital Heart Surgery Database harvest are also presented.

Cardiac Surgical Procedures↗
PubMed2002

Congenital Heart Surgery Nomenclature and Database Project: update and proposed data harvest.

In 1998, the first report of the Society of Thoracic Surgery (STS) National Congenital Heart Surgery Database reported the clinical features of 18 congenital heart categories. The report provided a significant amount of important information and also highlighted the strengths and weaknesses of the existing database. Following this report, the STS Congenital Heart Surgery Committee, in cooperation with the European Association of Cardio-Thoracic Surgery and the European Congenital Heart Surgeons Foundation, initiated the International Congenital Heart Surgery and Nomenclature Database Project. The goal was to begin the standardization of nomenclature and reporting strategies and establish the foundations for an international congenital heart surgery database. The first report of the International Congenital Heart Surgery Nomenclature Project was published in the Annals of Thoracic Surgery in April 2000. The current report outlines modifications to the minimal dataset, as well as the diagnosis and procedure short lists.

Cardiac Surgical Procedures↗
PubMed2002

Minimally invasive endoscopic repair of pectus excavatum.

OBJECTIVE: We report our initial 3 years 4 months' single institution experience in 31 consecutive patients with pectus excavatum treated with minimally invasive endoscopic pectus excavatum repair utilizing a modification of the 'Nuss' technique. METHODS: Under general anesthesia, a curved steel bar is individually shaped for each patient to match the ideal chest wall shape and is placed through an endoscopically created retrosternal tunnel between two bilateral midaxillary line 2-cm incisions. The tunnels initially go along the outside of the rib cage, under the pectoral muscles. At the level of the sternum, these tunnels go retrosternal and communicate with each other. The steel bar is passed with the convexity facing posteriorly, within a protective flat silastic drain. Under endoscopic guidance, the curved steel bar is passed through one tunnel, under the sternum, and out the other tunnel. Once positioned, the bar is turned over, thereby correcting the deformity. An epidural catheter provides perioperative pain relief. RESULTS: Minimally invasive endoscopic pectus excavatum repair has been performed on 31 patients (age: range 4.4-31.0 years, median 15.0 years, mean 14.5 years). Median hospital length of stay is 4 days (range 3-10 days, mean 4.6 days). Pneumothorax occurred in five patients requiring tube thoracostomy in three. One patient developed delayed bilateral pleural effusions requiring drainage. Two patients developed evidence of sterile seroma formation at the skin incision several months after minimally invasive repair of pectus excavatum. These seromas resolved with non-interventional conservative medical treatment. No other complications occurred. CONCLUSION: The minimally invasive endoscopic pectus repair is safe and effective and currently our procedure of choice for primary pectus excavatum in all ages. Endoscopic visualization facilitates the safe creation of the retrosternal tunnel. Short-term results have been excellent. Further follow-up will be necessary to determine long-term results.

Adolescent↗
PubMed2002

Aortic arch reconstruction without circulatory arrest: review of techniques, applications, and indications.

The majority of neonatal intracardiac repairs can now be performed with the use of low-flow cardiopulmonary bypass. However, aortic arch reconstruction still requires a period of circulatory arrest. Recently, a number of surgeons have reported techniques of limiting or completely avoiding circulatory arrest during arch reconstruction in an attempt to reduce the risk of neurologic injury. Several techniques are currently in use that have been successfully applied during biventricular repair and the Norwood operation for a wide range of aortic arch pathology including hypoplastic or interrupted aortic arch, the hypoplastic left heart syndrome, and its equivalents. These techniques maintain continuous low-flow cerebral perfusion via the innominate artery, directly or indirectly. In the last 2 years at the Montreal Children's Hospital (Montreal, Canada) we have consistently used such techniques for all arch reconstructions, including the Norwood operation, completely avoiding the use of circulatory arrest. These techniques are still in evolution with regard to flow rates, temperature, and safe period of low flow. Although the early results are encouraging, long-term follow-up with respect to neurodevelopmental outcome is essential to help us decide which techniques are optimal. This chapter provides an overview of the currently used techniques allowing cerebral perfusion during aortic arch reconstruction and summarizes our early experience at the Montreal Children's Hospital.

Aorta, Thoracic↗
PubMed2002

Fontan operation for patients with severe distal pulmonary artery stenosis, atresia, or a single lung.

In the absence of a ventricular pump, the status of the pulmonary circulation is crucial to the success of the Fontan operation. In an updated version (1999) of the optimal criteria for the Fontan operation, several of these criteria address the pulmonary circulation: pulmonary artery pressure, pulmonary vascular resistance, pulmonary artery size, and absence of significant pulmonary artery branch stenosis. This chapter reviews the role of the pulmonary circulation in a successful Fontan operation, with a particular emphasis on surgical techniques to repair severe distal or hilar pulmonary artery stenosis or atresia. The special situation of the patient with a single pulmonary artery is also addressed. Severe hilar pulmonary artery stenosis or atresia can be repaired by the technique of intrapulmonary pulmonary artery reconstruction with pericardial patch or tube and allow the successful completion of the Fontan operation. In the selected patient with a single pulmonary artery and optimal hemodynamics, the Fontan operation is possible with good outcome. However, further experience is needed in a larger number of patients to assess the long-term outcome of these treatment strategies.

Fontan Procedure↗
PubMedDate not supplied

Single aortic clamp versus partial occluding clamp technique for cerebral protection during coronary artery bypass: a randomized prospective trial.

UNLABELLED: Single aortic clamp (SAC) versus partial occluding clamp (POC) technique for the construction of proximal anastomosis has been suggested to provide better cerebral protection during coronary artery bypass grafting (CABG). The aim of this study was to assess this hypothesis in a prospective randomized trial. METHODS: Two hundred sixty-eight consecutive patients underwent CABG at a single institution. All patients were randomized to either SAC (Group S) or POC (Group P) for the construction of the proximal anastomosis. Myocardial protection consisted of multidose antegrade cold blood cardioplegia with topical cooling. The operations were performed using standard cardiopulmonary bypass support and moderate systemic hypothermia (29 to 32 degrees C). The incidences of neurological events, perioperative myocardial infarction (MI), and mortality were prospectively evaluated. RESULTS: The two groups were similar in mean age, gender, urgency of operation, and number of bypasses. Group S patients had a significantly longer cross-clamp (61 +/- 21 minutes [S] vs 44 +/- 13.8 minutes [P], p < 0.05) and bypass times (85 +/- 25 minutes [S] vs 74 +/- 19.7 minutes [P], p < 0.05). There were no differences in the number of perioperative MIs (Group S = 3 [2.3%]; Group P = 2 [1.5%], p = 0.50) or mortality (Group S = 2 [1.5%]; Group P = 3 [2.2%], p = 0.50). Two patients randomized to POC were switched to SAC intraoperatively because of severe calcification of the ascending aorta. In Group P, there were two strokes (1.5%) and two (1.5%) postoperative confusions versus none in Group S (relative risk = 2.0, p < 0.05, respectively). CONCLUSION: The SAC technique improved cerebral protection without any adverse effect on myocardial protection and postoperative outcome in patients undergoing CABG.

Aged↗
PubMedDate not supplied

Complete repair of concomitant interrupted aortic arch and partial anomalous pulmonary venous connection.

We report a rare case of concomitant presentation of partial anomalous pulmonary venous connection and type A interrupted aortic arch in a 4-week-old, 2.1 kg newborn. She presented in extremis and was found to have a closed ductus arteriosus with the entire left pulmonary venous return obstructed at its connection with the innominate vein. Emergent operative repair was performed in one-stage, consisting of aortic arch reconstruction and anomalous vein translocation. Postoperative recovery was unremarkable and the patient was discharged from hospital 12 days after operation.

Abnormalities, Multiple↗