Biomedical subjects

Christopher J Hudson

Publications and source records attributed to Christopher J Hudson.

3 recordsLinked to original sources

PubMed2005

Hyperthyroidism presenting as isolated tricuspid regurgitation and right heart failure.

Although hyperthyroidism has many signs and symptoms, right heart failure can occasionally be the main presenting symptom. We describe the case of a previously healthy 42-year-old woman whose chief complaint was progressive bilateral lower extremity edema. The echocardiogram revealed right atrial dilatation and moderate-to-severe tricuspid regurgitation. Results of laboratory studies were consistent with hyperthyroidism. Thyroid ablation resulted in permanent resolution of symptoms and resolution of tricuspid incompetence on echocardiography. In a case of isolated, unexplained tricuspid regurgitation, it is important to consider indolent hyperthyroidism in the differential diagnosis.

Adult↗

PubMed2004

Brugada electrocardiographic pattern elicited by inadvertent flecainide overdose.

In a 70-year-old man, without clinical suggestion of the hereditary form of the Brugada syndrome, severe flecainide overdose resulted in profound widening of the QRS complex and the development of ST-T abnormalities typical of the Brugada sign. Serial ECGs recorded over a 5-day period revealed a parallel pattern of dynamic intraventricular conduction defect and ST-segment elevation. Resolution of ST-segment elevation lagged behind resolution of the QRS widening by 16-20 hours. Despite the marked Brugada abnormality no arrhythmia occurred and the patient recovered without complications.

Aged↗

PubMedDate not supplied

His bundle block.

In patients with narrow QRS complexes, atrioventricular block is usually localized to the AV node, and it is frequently benign. The more distal intra-His bundle blocks are rare, potentially malignant, and difficult to recognize. This case report illustrates how His bundle block can be diagnosed by analyzing the effects of certain maneuvers on the heart rate. Paradoxically, exercise and atropine tend to provoke His bundle block, whereas carotid massage may release it. Implantation of a permanent pacemaker is generally indicated.

Aged↗