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Biomedical subjects

Christopher Longbottom

Publications and source records attributed to Christopher Longbottom.

3 recordsLinked to original sources

Three-dimensional terahertz pulse imaging of dental tissue.

There are unresolved clinical problems that require the provision of accurate 3-D images of tissue structures such as teeth. In particular, measurements of dental enamel thickness are necessary to quantify problems associated with enamel erosion, yet currently there is no nondestructive method to obtain this information. We present a method that relies on the use of pulsed terahertz radiation to gain 3-D information from dental tissues. We discuss results from 14 samples and demonstrate that we can reliably and accurately quantify enamel thickness. We show that in a series of 22 surfaces, we can image pertinent subsurface features 91% of the time. Example images are shown where structures in teeth at depth are rendered accurate to within 10 microm. We discuss issues that arise using this imaging method and propose ways in which it could be used in clinical practice.

Diagnostic Imaging↗

Quantifying dental inequality--developing the methodology.

OBJECTIVE: To develop a simple quantitative measure of dental health inequality. METHOD: Define equality based on statistical theory and construct a formula to compare actual and theoretical disease distributions. RESULT: A new index (DHII) is proposed, based on the ratio of the distribution of the actual disease to a (theoretical) Poisson distribution. An example using caries data is provided. CONCLUSION: Use of DHII will allow quantitative measurement of dental health inequality.

Binomial Distribution↗

Terahertz pulse imaging: a pilot study of potential applications in dentistry.

The improvement in the detection of caries offers the possibility for dramatic improvement in dental healthcare. Current caries detection rates suggest that there may be scope for improvement. This paper describes a preliminary study to examine applications of terahertz pulse imaging (TPI) to caries detection. We present results for the detection of early stage caries in the occlusal enamel layer of a range of human tooth cross sections using TPI. Higher attenuation of terahertz radiation was observed in carious enamel as compared with healthy enamel. Hypomineralised enamel had different absorption spectra and contrast compared to carious enamel in TPI images. These results have important implications for extending TPI to other medical imaging applications where both early diagnosis and safety issues are important.

Dental Caries↗