Christopher W Myers | PubMed Health

PubMed2005

ProtoMatch: a tool for analyzing high-density, sequential eye gaze and cursor protocols.

ProtoMatch is a software tool for integrating and analyzing fixed-location and movement eye gaze and cursor data. It provides a comprehensive collection of protocol analysis tools that support sequential data analyses for eye fixations and scanpaths as well as for cursor "fixations" (dwells at one location) and "cursorpaths" (movements between locations). ProtoMatch is modularized software that integrates both eye gaze and cursor protocols into a unified stream of data and provides an assortment of filters and analyses. ProtoMatch subsumes basic analyses (i.e., fixation duration, number of fixations, etc.) and introduces a method of objectively computing the similarity between scanpaths or cursorpaths using sequence alignment. The combination of filters, basic analyses, and sequence alignment in ProtoMatch provides researchers with a versatile system for performing both confirmatory and exploratory sequential data analyses (Sanderson & Fisher, 1994).

Eye Movements↗

PubMed2002

Carotid distensibility characterized via the isometric exercise pressor response.

Distensibility of the large elastic arteries is a key index for cardiovascular health. Distensibility, usually estimated from resting values in humans, is not a static characteristic but a negative curvilinear function of pressure. We hypothesized that differences in vascular function with gender and age may only be recognized if distensibility is quantified over a range of pressures. We used isometric handgrip exercise to induce progressive increases in pressures and carotid diameters, thereby enhancing the characterization of distensibility. In 30 volunteers, evenly distributed by gender and age across the third to fifth decades of life, we derived pulsatile distensibility slopes as a function of arterial pressure for a dynamic distensibility index and compared it with a traditional static index at a reference pressure of 95 mmHg. We also assessed intima-media thickness (IMT). We found that women had greater distensibility slopes within each decade, despite comparable IMT. Furthermore, declines in distensibility slope with increasing age were correlated to increased IMT. The static distensibility index failed to show gender-related differences in distensibility but did show age-related differences. Our results indicate that gender- and age-related differences can be manifest even in young, healthy adults and may only be identified with techniques that assess carotid distensibility across a range of pressures.

Adult↗