[Relation between Beta-2-glycoprotein I and hepatitis B virus surface antigen].
OBJECTIVE: To clarify the binding character between Beta-2-glycoprotein I (Beta-2-GPI) and HBsAg. METHODS: Beta-2-GPI was purified from human plasma and labelled with biotin. Solid phase enzyme linked absorbance assay was used to investigate its binding with HBsAg. RESULTS: Biotinylated Beta-2-GPI was found to bind HBsAg and the reaction could be inhibited by excess unlabelled Beta-2-GPI. CONCLUSIONS: Beta-2-GPI may play a role in hepatitis B virus infection.
Binding Sites↗