Biomedical subjects

Cihangir Kaymaz

Publications and source records attributed to Cihangir Kaymaz.

21 records · Page 2Linked to original sources

PubMed2002

Measurement of aortic valve anatomic regurgitant area using transesophageal echocardiography: implications for the quantitation of aortic regurgitation.

BACKGROUND: Various echocardiographic methods for the assessment of the severity of the aortic regurgitation (AR) by have been described with no general consensus. AIM: To assess the feasibility and reproducibility of direct planimetric measurement of the end-diastolic gap between aortic cusps on the transesophageal echocardiography (TEE) images in patients with AR. We also analyzed the correlation of this anatomic aortic regurgitanty area with angiographic AR severity. METHODS: Ninety patients (38 males, 52 females, mean age 41 +/- 24 years) with AR who underwent TEE and contrast aortography in a single institution. The AR was graded angiographically as mild (n = 45), moderate (n = 31), and severe (n = 14). The anatomic regurgitant area was measured on the end-diastolic short-axis TEE images of the aortic valve by planimetering the central gap bordered by the commisural edges of the aortic cusps. RESULTS: The intraobserver and interobserver variability for the measurement of aortic anatomic regurgitant area were small (mean absolute differences 0.01 +/- 0.01 cm(2), and 0.015 +/- 0.013 cm(2), respectively). The average values of anatomic regurgitant area for angiographically mild, moderate, and severe AR were 0.15 +/- 0.05 cm(2), 0.30 +/- 0.08 cm(2), and 0.68 +/- 0.33 cm(2), respectively (P <.001). When the anatomic regurgitant area was graded as small (> 0.2 cm(2)), moderate (> 0.2 and > 0.4 cm(2)) and large (> 0.4 cm(2)), the sensitivity, specificity, positive and negative predictive value, and the diagnostic accuracy for predicting the angiographically mild AR were 85%, 97%, 97%, 87%, and 91%, respectively. For the moderate angiographic AR the same values were 84%, 92%, 81%, 93%, and 90%, and for the severe angiographic AR they were 98%, 93%, 93%, 98% and 97%. CONCLUSION: The planimetric measurement of aortic anatomic regurgitant area by TEE is feasible and reproducible for the assessment of the severity of AR.

Adolescent↗

PubMed2002

Severe mitral regurgitation may prevent mural thrombus formation within the left ventricle with systolic dysfunction.

The protective effect of severe mitral regurgitation (MR) against left atrial thrombus formation has been well documented. It was also proposed that severe MR may prevent thrombus formation within the left ventricle (LV) with systolic dysfunction. Therefore, we investigated whether ischemic MR prevents thrombus formation within the LV in patients with systolic dysfunction. The study population was comprised of 1313 patients (1133 males, 180 females, age 56+/-18) with ischaemic LV dysfunction documented by coronary angiography and left ventriculography. None of the patients had a history of chronic anticoagulation. Epicardial coronary arteries were normal in 91 patients, and single-vessel, two-vessel, and triple-vessel disease were detected in 328, 330, and 564 patients, respectively. Left ventricular thrombus and severe MR were detected in 191 (14.5%) and 125 (9.5%) patients, respectively. Overall incidence of LV thrombus was lower in patients with severe MR than in patients without severe MR (4% vs 15.6%, OR: 0.2, P<0.001). Severe MR compared with absence of severe MR was associated with a lower incidence of LV thrombus both in patients with ischemic dilated cardiomyopathy (6.8% vs 34.2%, OR: 0.19, P<0.001), and in patients with aneurysm (3% vs 18%, OR: 0.14, P<0.0001) involving anterolateral, septal and/or apical LV segments. A similar trend without statistical significance was also observed in patients with dyskinesia (4.7% vs 16%, OR: 0.26, P=0.1) related to anterolateral, septal and/or apical LV segments. However, MR had no impact on the incidence of LV thrombus in patients with aneurysm or dyskinesia related to posterior and/or inferior segments (3.7% vs 3%, OR: 1.2, P>0.05). In conclusion, severe MR seems to prevent LV mural thrombus formation in patients with ischemic dilated cardiomyopathy, and in patients with aneurysm related to anterolateral, septal, and/or apical LV segments. This relative risk reduction may be associated with diastolic volume overloading due to severe MR which may overcome stagnation and a procoagulant state within the LV with severe systolic dysfunction.

Adult↗

PubMedDate not supplied

Cardiac hydatid cysts: surgical treatment and results.

From 1991 to 2000 six patients with intracardiac echinococcosis underwent surgical treatment. Four patients were females and two were males, age of the patients ranged from 20 to 68 years. Two patients had symptoms, all patients were diagnosed as a component of multi-organ echinococcosis and three of them underwent operation before. They were examined serologically and echocardiographically. Cardiac hydatidosis were diagnosed in right ventricle (in three cases), left ventricle (in one case), and interventricular septum (in two cases). Sternotomy was the approach used and all patients were operated on using cardiopulmonary bypass. Intraoperative rupture did not occur. There was no operative mortality, the only morbidity was complete atrioventricular block necessitating VVD pacemaker implantation in the patient with hydatid cyst involving the basal interventricular septum. All patients were followed by medical treatment with albendazole (400 mg/day) and no recurrences were reported in the late follow-up.

Adult↗