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Cinzia Casieri

Publications and source records attributed to Cinzia Casieri.

2 recordsLinked to original sources

Large surface mapping by a unilateral NMR scanner.

The nuclear magnetic resonance (NMR) surface scanner, which provides images of sample surfaces larger than the probe dimension, has been realized using a single-sided device. Although conditioned by distortion effects originated by convolution between the sensitive volume of the probe and the space structures to be imaged, the scanner is able to provide images with good spatial resolution. The images obtained by the surface scanner can be made sensitive to relaxation parameters, magnetization or molecular self-diffusion; also, the dimension perpendicular to the sample surface can be scanned by varying the depth from which the probe detects the sample signal. It may scan surfaces arbitrarily large and with some degree of curvature. This aspect, together with the noninvasive characteristic of the apparatus, indicates that the surface scanner could be used profitably in the field of cultural heritage, where it could provide NMR maps of frescos, paintings on wood, marble artifacts, books and others.

Equipment Design↗

Bayesian analysis of in vivo dynamic 13C-edited 1H images.

We propose an application of a Bayesian methodology to dynamic MR images of protons J-coupled to 13C nuclei for monitoring the in vivo 13C-glucose uptake of mouse brain. The very low population of these protons and the random noise make the analysis of these images extremely difficult. The proposed method restores the images and provides an "activation" map of the mouse brain by means of a hypothesis testing procedure. The restoration step is performed in the Bayesian framework so that among the other advantages of a stochastic approach, it is possible to model spatial and temporal information about neighboring pixels. This leads to a restoration procedure able to reduce the noise level while preserving the information about the edges of signal areas. Based on the restored images, the testing procedure provides us with a reliable map of pixels characterized by the 13C-glucose uptake.

Animals↗