Biomedical subjects
Publications and source records attributed to Cisco Bee.
The PdCl(2)-catalyzed cyclization of alpha-alkoxy dienones leads to 2-hydroxycyclopentenones, whereas the Pd(OAc)(2)-catalyzed reaction leads to cross-conjugated cyclopentenones through an oxidative process. [reaction: see text]
[reaction: see text]. Propargyl vinyl ketones that are derived from the addition of 1-lithio-1-methoxymethoxy-2-ynes to morpholino enamides undergo isomerization followed by cyclization to alpha-methylene cyclopentenones upon exposure to silica gel.
[reaction: see text] A triply convergent synthesis of alpha-methylene cyclopentenones has been demonstrated in which an intermediate C,O-dianion is formed and trapped on carbon by electrophiles.