Biomedical subjects

Clément Pinquier

Publications and source records attributed to Clément Pinquier.

3 recordsLinked to original sources

PubMed2005

Specific genetic disorders and autism: clinical contribution towards their identification.

Autism is a heterogeneous disorder that can reveal a specific genetic disease. This paper describes several genetic diseases consistently associated with autism (fragile X, tuberous sclerosis, Angelman syndrome, duplication of 15q11-q13, Down syndrome, San Filippo syndrome, MECP2 related disorders, phenylketonuria, Smith-Magenis syndrome, 22q13 deletion, adenylosuccinate lyase deficiency, Cohen syndrome, and Smith-Lemli-Opitz syndrome) and proposes a consensual and economic diagnostic strategy to help practitioners to identify them. A rigorous initial clinical screening is presented to avoid unnecessary laboratory and imaging studies. Regarding psychiatric nosography, the concept of "syndromal autism"--autism associated with other clinical signs should be promoted because it may help to distinguish patients who warrant a multidisciplinary approach and further investigation.

Autistic Disorder↗

PubMed2005

[Elder abuse and emergency care units].

Elder abuse could present with various aspects: physical, psychological, sexual aggression, embezzlement, neglect or self-neglect. According to epidemiological studies, between two and ten percent of the elderly population are concerned, but only few cases are reported, but this rate will likely increase with the growing elderly population. This paper highlights the risk factors for elder abuse. Most of the time, abuse is perpetrated by family members or close relatives, who often are dependent on the victim. It could also be a usual mode of interrelationship in some families, in which careful attention should be paid for the risk of abuse against the younger generation. In emergency care units, physicians infrequently report elder abuse because they fear offending patients or families and believe they do not have appropriate assessment tools. Victims often have low self-esteem, do not want to admit their vulnerability and do not imagine a different way for living with their aggressor. However, assessment and management of elder abuse could be supportive if all members of the team are concerned with this issue and have received appropriate information and education. The best approach is to focus on both the patient and the caregiver and to accept that there are no other tool to reveal abuse than to obtain the confidence of the patient. Every people concerned should remain respectful with each individual and not experience feelings of guilt in this upsetting situation.

Aged↗

PubMed2003

[Hysteria and aging].

In the elderly, the manifestations of hysteria can take uncommon aspects such as durable conversion disorders for which a diagnosis is difficult in the context of polypathology, dissociative symptoms looking like some dementia syndromes, noisy psychiatric symptomatology with, in particular, severe depressive episodes or hallucinations. These disorders can appear without a context of histrionic personality. The evolution of hysterical disorders during life is not well known. First of all, because the nosographic systems are not constant and, secondly, because the disorders themselves can vary when observed at different times. The aging subject is exposed to an increasing symptomatology or conversely, to an improvement due to the waekening of the narcissism. It is also possible that a continuum could be established from hysterical symptoms in the adulthood to delusions or hallucinations in the elderly. The relation with the old hysteric subject must be marked by empathy and by the conviction that improvement will only lead back to a basal symptomatology.

Aged↗