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Claus Møldrup

Publications and source records attributed to Claus Møldrup.

9 recordsLinked to original sources

Public acceptance of drug use for non-disease conditions.

OBJECTIVE: This article deals with the issue of ordinary healthy people using drugs to improve or enhance non-disease conditions. The objective is to illuminate the extent of public acceptance of this practice. RESEARCH DESIGN AND METHODS: The results are based on two studies: a classically structured telephone interview with 961 Danes in 1999 and an Internet questionnaire survey of 2735 Danes in 2003. The two studies cannot be compared due to differences in recruitment and methodology. RESULTS: Based on basic descriptive statistics, the studies show substantial public acceptance of the use of drugs for non-disease conditions. Men in particular look favourably on the use of drugs by healthy individuals. People with less education find this type of drug use unacceptable to a greater extent than those with more education, who are more positive. If we look at political affiliation, a pattern emerges. People who did not vote or voted for one of the left-wing parties are less likely to accept this type of drug use. The extent to which people work with drugs professionally does not seem to influence the extent to which they are positive or negative about this type of drug use. CONCLUSION: The implications of this development encompass a wide range of concerns, from the individual risk of side effects to general issues concerning the prioritisation of health care resources. The results need more attention, including further studies, professional consideration and health policy decisions.

Adolescent↗

No cure, no pay.

Explore the source record for details and available documents.

Drug Industry↗

Feasibility of collecting diary data from asthma patients through mobile phones and SMS (short message service): response rate analysis and focus group evaluation from a pilot study.

BACKGROUND: Self-management of asthma may improve asthma outcomes. The Internet has been suggested as a tool for the monitoring and self-management of asthma. However, in a recent study we found that a Web interface had some disadvantages and that users stopped using the application after a short while. OBJECTIVE: The primary objective of this study was to evaluate, from a user perspective, the feasibility of using short message service (SMS) for asthma diary data collection through mobile phones. The secondary objective was to investigate patient compliance with an SMS diary, as measured by response rates over time. METHODS: The study included quantitative response rate data, based on SMS collection, and qualitative data from a traditional focus group setting. In a period of 2 months, the participants received 4 SMS messages each day, including a medication reminder, a request to enter peak flow, data on sleep loss, and medication dosage. Participants were asked to reply to a minimum of 3 of the messages per day. Diary inputs were collected in a database and the response rate per patient was expressed as the number of diary inputs (SMS replies) divided by diary requests (product of number of days in the study and the number of diary questions per day) for each participant. After the study period, the participants were invited to a focus group interview addressing the participants' attitudes to their disease, their experience with the SMS asthma diary, and their future expectations from the SMS asthma diary. RESULTS: Twelve patients with asthma (6 males, 6 females) participated in the data collection study. The median age was 38.5 (range: 13-57) years. The median response rate per patient was 0.69 (range: 0.03-0.98), ie, half the participants reported more than about two thirds of the requested diary data. Furthermore, response rates were relatively steady during the study period with no signs of decreasing usage over time. From the subsequent focus group interview with 9 users we learned that, in general, the participants were enthusiastic about the SMS diary--it became an integrated part of their everyday life. However, the participants wished for a simpler diary with only one SMS message to respond to and a system with a Web interface for system customization and graphical display of diary data history. CONCLUSION: This study suggests that SMS collection of asthma diary data is feasible, and that SMS may be a tool for supporting the self-management of asthma (and possibly other chronic diseases) in motivated and self-efficacious patients because mobile phones are a part of people's everyday lives and enable active requests for data wherever the patient is. The combination of SMS data collection and a traditional Web page for data display and system customization may be a better and more usable tool for patients than the use of Web-based asthma diaries which suffer from high attrition rates.

Adolescent↗

The use of the terms 'lifestyle medicines' or 'lifestyle drugs'.

AIM: over the last 10 decades, 'lifestyle medicines' or 'lifestyle drugs' have been used with increasing frequency by journalists, politicians, authorities and to some extent by scientists. The objective of this paper is to analyse the quantity and quality of the use of these terms and discuss the implications associated with the labelling of indications and products as lifestyle medicines or lifestyle drugs. METHODS: The findings in this paper are based on an extensive literature review in the databases Medline, Pubmed, Embase and the two most frequently used search engines altavista.com and google.com, as well as the media database LexisNexis. RESULTS: In the period 1978 to August 2003, the term 'lifestyle medicines/drugs' has appeared 3174 times in English language media. In total, 23 different definitions are presented in the scientific literature. CONCLUSIONS: The review of the scientific literature shows that no widely accepted definition of the terms 'lifestyle medicines' or 'lifestyle drugs' exists. Nevertheless the terms have appeared more than 3000 times in the media (2600 times since 1998), which means that in most cases, the use of the terms 'lifestyle medicines' or 'lifestyle drugs' are based on the authors' own assumptions and values. This is problematic, not only in terms of a discourse, where no one knows what forms the basis of the discussion, but also because this at best leads to an uninformed discussion and at worst to harmful conclusions that might stigmatise and discriminate patients. Based on these findings, this paper argues that a clear, widely accepted definition of the terms 'lifestyle medicines' or 'lifestyle drugs' is essential to avoid potential misunderstandings that might lead to discrimination in the rationing of healthcare resources or stigmatisation of patients.

Denmark↗

[The importance of pharmacogenetics in the primary health care sector].

This paper describes drug development based on pharmacogenetic experiences and the inherent implications for the health professions in the primary health care service sector. Pharmacogenetics involves increased demands for competence in extracting the newest knowledge for the benefit of the patients, and the need for advising patients about of usage and the ethical aspects of drugs, which are prescribed on the basis of the genetic profile of a specific patient. International experiences show that the health professions in general are poorly trained to handle this task. There is no evidence that the health professionals in the primary health care service sector in Denmark are any better prepared. This paper concludes that if the positive prospects of pharmacogenetics are to benefit patients, systematized training of the health professionals in the primary health care sector is needed.

Clinical Competence↗