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Clayton Young

Publications and source records attributed to Clayton Young.

2 recordsLinked to original sources

Miniaturized chest compressor.

BACKGROUND: Current American Heart Association guidelines call for continuous manual chest compressions for cardiopulmonary resuscitation. Chest compressions maintain critical levels of forward blood flow, including blood flow to the myocardium during cardiac arrest, to allow for successful resuscitation. The demand on rescuers is to ensure that compression is consistent, with appropriate force and depth, often under difficult conditions of rescue, evacuation, and transport. It is also of great moment that fatigue of the rescuer adversely affects outcomes. This evaluation was to compare two pneumatically driven devices, the Michigan Thumper (Michigan Instruments, Grand Rapids, MI), as an industrial standard, and the miniaturized chest compressor. METHODS: On a porcine model of cardiopulmonary resuscitation, alternating current fibrillation was induced for 7 mins, followed by 5 mins of chest compression. Arterial and right atrial pressures and end-tidal CO2 were measured. Coronary perfusion pressure was calculated as the difference between compression end-diastolic arterial pressure and right atrial pressure. RESULTS: Threshold levels of coronary perfusion pressure (>15 mm Hg) and end-tidal CO2 (>10 mm Hg) for successful defibrillation were maintained with the miniaturized chest compressor. Consistently greater coronary perfusion pressure and end-tidal CO2 values were achieved with the miniaturized chest compressor in comparison with the Thumper. CONCLUSION: The miniaturized chest compressor has the important potential advantage of minimal weight and, therefore, portability, without any reduction in effectiveness. To the contrary, it is potentially more effective than the much larger and heavier industry standard for maintaining circulation.

Animals↗

Amplitude spectrum area: measuring the probability of successful defibrillation as applied to human data.

OBJECTIVE: The objective of our study was to examine the effectiveness of an electrocardiographic predictor, amplitude spectral area (AMSA), for the optimal timing of defibrillation shocks in human victims of cardiac arrest. Based on the spectral characteristics of ventricular fibrillation potentials, we examined the probability of successful conversion to an organized viable rhythm, including the return of spontaneous circulation. The incentive was to predict the likelihood of successful defibrillation and thereby improve outcomes by minimizing interruptions in chest compression and minimizing electrically induced myocardial injury due to repetitive high-current shocks. DESIGN: Observational study on human electrocardiographic recordings during cardiopulmonary resuscitation. SETTING: Medical research laboratory of a university-affiliated research and educational institute. PATIENTS: Victims of out-of-hospital cardiac arrest. INTERVENTIONS: Iteration of electrocardiographic records, representing lead 2 equivalent recordings on 108 defibrillation attempts with an automated external defibrillator, of 46 victims of cardiac arrest due to ventricular fibrillation. MEASUREMENTS AND MAIN RESULTS: Three seconds of ventricular fibrillation, recorded immediately preceding delivery of a shock, were analyzed utilizing the AMSA algorithm. AMSA represents a numerical value based on the sum of the magnitude of the weighted frequency spectrum between 3 and 48 Hz. The greater the AMSA value, the greater was the probability of reversal of ventricular fibrillation. At an AMSA value of >13.0 mV-Hz, successful defibrillation yielded a sensitivity of .91 and a specificity of .94. CONCLUSION: AMSA predicts the success of electrical defibrillation with high specificity. AMSA therefore serves to minimize interruptions of precordial compression and the myocardial damage caused by delivery of repetitive and ineffective electrical shocks.

Databases, Factual↗