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Clyde W Yancy

Publications and source records attributed to Clyde W Yancy.

56 records · Page 4Linked to original sources
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Overview of B-type natriuretic peptide as a blood test. Roundtable discussion.

A roundtable discussion was convened in December 2005 to discuss current and future applications of blood B-type natriuretic peptide testing in the diagnosis and treatment of cardiovascular disease. Dr. Peter McCullough, consulting cardiologist and Chief of the Division of Preventive Medicine at William Beaumont Hospital in Royal Oak, MI, chaired the discussion. Dr. Christian Mueller, consultant cardiologist and active researcher in the area of cardiac natriuretic peptides at the Department of Internal Medicine, University Hospital, Basel, Switzerland; and Dr. Clyde Yancy, Associate Dean for Medical Affairs at the University of Texas Southwestern Medical Center, Dallas, TX, participated in the discussion.

Cardiovascular Diseases↗
PubMedDate not supplied

Novel therapies for heart failure: vasopressin and selective aldosterone antagonists.

Despite favorable improvements in mortality, heart failure (HF) remains a problematic illness due to the ever-present burden of hospitalization. Clearly, novel treatment strategies are needed. This review focuses on two newer pharmacologic targets: arginine vasopressin and aldosterone. Arginine vasopressin receptor antagonists will most likely serve as an adjunct to or replacement of standard diuretic therapy in selected patients. The safety and efficacy of chronic therapy with oral arginine vasopressin receptor antagonists in large groups of congestive HF patients is currently under investigation. Aldosterone antagonism is emerging as a treatment of severe congestive HF. Recent large-scale clinical trials using aldosterone antagonists have proven that those with HF or left ventricular dysfunction postmyocardial infarction derive a survival benefit from aldosterone antagonism. Whether aldosterone antagonism should be prescribed in all patients with HF is unclear; however, in carefully selected and managed patients, aldosterone antagonism is helpful.

Heart Failure↗