Dietary guidelines vs beverage guidance system.
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Animals↗
Biomedical subjects
Connie Weaver
Publications and source records attributed to Connie Weaver.
The 2005 Dietary Guidelines Advisory Committee: developing a key message.
The 2005 Dietary Guidelines Advisory Committee used an evidence-based approach to evaluate the science base for the relationships of diet and physical activity and health. Nine key messages and corresponding conclusions were included in the 2005 Dietary Guidelines Advisory Committee report. This article describes the development process, scientific basis, and specific recommendations for one of the key messages.
Age Factors↗
Profiling and quantification of isoflavonoids in kudzu dietary supplements by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry.
The kudzu vine (Pueraria sp.) is a rich source of isoflavones. Dietary supplements based on kudzu have become commercially available. In the present study, liquid chromatography coupled with negative and positive electrospray ionization tandem mass spectrometry (MS/MS) and diode array detection (DAD) has been used for the detection and characterization of isoflavonoids in kudzu dietary supplements (KDS). The MS/MS spectrum of the protonated ion of puerarin showed characteristic product ions of the C-glycoside unit itself, whereas daidzin generated an abundant Y(0)(+) aglycon ion in its product ion spectrum. A base peak due to the loss of 120 Da [M + H - 120](+) is the diagnostic ion for C-glycosides. Neutral loss scans allowed for the detection of other C- and O-glycosides in the methanolic extract of KDS, and their structures have been proposed. The concentration of isoflavonoids in the methanolic extract of commercially available KDS was quantified by using DAD-HPLC. Puerarin, rather than daidzin, was the most abundant component (8.44-30.60 mg/capsule) in commercially available KDS.
Chromatography, High Pressure Liquid↗