Biomedical subjects

Cristina Simionescu

Publications and source records attributed to Cristina Simionescu.

4 recordsLinked to original sources

PubMed2006

[Conjunctival changes in pseudoexfoliative syndrome].

PURPOSE: Histopathologic study of conjunctival biopsy specimens in patients with or without exfoliation syndrome and mature cataract to reveal the presence of exfoliative material. MATERIAL AND METHOD: There were studied a group of patients with different ages who needed surgical cataract extraction; all patients were examined preoperative for the presence of exfoliation syndrome. The conjunctival biopsy specimens were obtained at the end of cataract surgical procedure in eyes both with exfoliation syndrome and in fellow eyes without clinical evidence of the disease. RESULTS: It has been recorded the presence of the exfoliative material in eyes both with exfoliation syndrome and in fellow eyes without clinical evidence of the disease. CONCLUSIONS: Conjunctiva appears to be an independent source of exfoliation material with early detection in preclinical stage of exfoliation syndrome in fellow eyes that appeared to be clinically unaffected.

Adult↗

PubMed2006

[Uveal melanoma].

The paper present a clinic and histological study, including all cases of uveal malignant tumours, hospitalized in Ophthalmological Clinic of Craiova in the last 15 years. The follow-up period of cases were 4 years. The diagnosis was established by clinic and paraclinic examination (imaging methods-- MRI, CT, Echo) and histologic examination. The histologic examination has been done for all cases. There were investigated several parametres: tumour cytology, the level of pigmentation, intravascular embolus, sclera infiltration, vascular invasion, vascular pattern, tumoral necrosis, mitotic activity. The histologic aspects of tumoral progression were: the high level mitotic activity, high surface area of intratumoral necrosis, the infiltrative process to the vessels, sclera, and ciliary body. The arcuat and network vascular patterns were involved in the systemic metastasis and local invasion. The most predominant type of cellularity related with a severe evolution of cases were the epithelioid cells and the mixed type cells.

Adult↗

PubMed2005

[Neovascular glaucoma--retrospective study].

The paper realized the retrospective evaluation of all cases of neovascular glaucoma hospitalized in Clinic of Ophthalmology of Craiova in the last 15 years. Neovascular secondary glaucoma represents 3,9% of all glaucomas. The most important etiologic factors were the central venous occlusion, diabetic retinopathy, carotid occlusion, intraocular tumors, chronic uveitis, Fuchs heterochromy. Neovascular secondary glaucoma is characterized by important hypoxic tissues destructions, presented of all levels that lead to neovessels formation with irreversible anatomic and functional losing of ocular globe. The identification of neovascular glaucoma causes and their treatment is important to prevent that diseases.

Adult↗

PubMed2004

[Ocular parasitosis--particular aspects].

The goal of this study cases are presented in this study. The first case was emphasized in a patient with an epibulbar tumor and the second case was diagnosed with Toxocara Canis. In both cases the ophthalmoscopic images and the clinical evolution were unusual on the other hand etiological diagnosis in both cases was difficult. In the first case, the surgical procedure was effective, but in the second case the specific antiparasitic treatment could not stop the evolution of corioretinal's lesions; it required laser therapy.

Adult↗