D A Andrewes | PubMed Health

PubMed1983

Rubella immunisation: whose baby?

Only half of girls aged from 11 to 14 years in a new town practice of 11 200 patients were recorded as immunised against rubella in 1979. The practice then assumed responsibility for its rubella immunisations and in four years, by using an age-sex register, achieved a 91% uptake of vaccine in the under 14s. In the over 14s, the practice reduced the number of "rubella risk" patients from 49% to 16%. It is suggested that general practitioners are best placed to implement the rubella immunisation programme successfully, though they will need to be renumerated adequately for this time consuming work.

Adolescent↗

PubMed1981

Trimethoprim and co-trimoxazole in the treatment of acute urinary tract infections: patient compliance and efficacy.

Patient compliance and drug efficacy and side-effects were compared in two groups of patients with symptoms of acute lower urinary tract infections. One group was treated with trimethoprim, one tablet (300 mg) once a day, and the other with co-trimoxazole, two tablets (160 mg trimethoprim, 800 mg sulphamethoxazole) twice a day; both treatments were prescribed for seven days. Patient compliance was significantly greater with trimethoprim: corrected percentage compliance rates were 97.5 per cent for trimethoprim and 79.1 per cent for co-trimoxazole (p<0.05). Trimethoprim and co-trimoxazole were of equivalent effectiveness in the control of symptoms. Side-effects were more frequent with co-trimoxazole, but the difference was not significant.

Acute Disease↗