Biomedical subjects
D A Boon
Publications and source records attributed to D A Boon.
[Big spleen, big problems].
The history of a Moroccan girl is described with splenomegaly, lymphadenopathy and pancytopenia after a holiday in her native country. Bone marrow smears were considered negative for Leishmaniasis in four different laboratories. All other diagnostic options could also not be confirmed. Reexamination of the bone marrow smears in a laboratory for tropical diseases revealed Leishmania donovani organisms. Treatment with sodium antimony gluconate was successful. Epidemiology, symptoms and diagnostic problems are discussed.
Medical adventure in Nepal.
In 1977 a request for teaching of otologic surgery from a Nepalese doctor to a Canadian colleague resulted in Doctor David Boon and his wife, Joan, travelling to Nepal in February, 1979, as volunteers. They participated in the "Lions Club of Kathmandu First Free Ear Camp" sponsored jointly by the International Sound Foundation Society and the Lions Club of Kathmandu. Fifteen hundred patients were seen and otosclerosis was one of the commonest ear diseases encountered. Adhesive otitis media with attic cholesteatoma was prevalent and a few cases of childhood serous otitis media were diagnosed. Severe sensorineural hearing loss was also prevalent and related to heredity, post febrile illness, and ototoxic drugs. Seventy surgical procedures were performed consisting of mastoidectomy, stapes reconstruction, tympanoplasty and myringotomy.
Testosterone production by XYY subjects.
A study of plasma concentration (P1T, ng/ml), metabolic clearance rate (MCRT, L/day) and blood production rate (PBT, mg/day) was done on seven XYY subjects of various ages and four pair-matched control XY subjects by a radioinfusion technique of 1,2-3H-testosterone. Although MCRT showed no significant difference between the groups, P1T and PBT were significantly lower (P less than 0.05) in XYY subjects. Therefore, increased aggressive behavior of the XYY subjects can not be attributed to increased levels or production rates of testosterone.
Plasma testosterone in men: variation, but not circadian rhythm 14 .
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Conjugated and unconjugated plasma androgens in normal children.
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Characterization of estriolglucosiduronic acid formed in vitro by human liver.
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Aggressiveness and testosterone measures in man.
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