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Biomedical subjects

D A Danielson

Publications and source records attributed to D A Danielson.

18 recordsLinked to original sources
PubMed1987

The massacre of MASSCARE. Dukakis' health-insurance plan and why it was defeated.

The authors critique the health-insurance plan proposed by Governor Michael Dukakis, and recount the uproar that followed its introduction into the Massachusetts legislature this past fall. With Dukakis having emerged as a leading contender for the Democratic presidential nomination, and with much hope for fundamental reform of our nation's health-care system hinging on the outcome of this year's elections, the plan, and its fate, may well provide a taste of things to come.

Government↗
PubMed1984

Drug-induced blood disorders.

A case-history study of drug-induced blood disorders (pancytopenia, hemolytic anemia, thrombocytopenia, and granulocytopenia) was carried out at the Group Health Cooperative of Puget Sound, a health maintenance organization with more than 200,000 members, for the ten-year period from 1972 through 1981. During this time, only 26 instances of hospitalization for such disorders were thought to be definitely, probably, or possibly due to drugs other than antitumor agents. The rate was of the order of one per 100,000 person-years at risk. Only quinidine/quinine and sulfa-containing drugs were implicated in more than one case.

Adolescent↗
PubMed1984

Drug toxicity and hospitalization among lithium users.

Among a cohort of 921 outpatients less than 65 years of age at Group Health Cooperative of Puget Sound who took lithium during a 5-year period, lithium-associated toxicity leading to hospitalization was rare. In only one case (muscle fasciculation) was lithium directly implicated as the cause of hospital admission. In five cases described in detail (one case each of hyperparathyroidism, vasculitis, edema, brain stem infarction, and subarachnoid hemorrhage), an etiologic connection with lithium exposure was considered unlikely but could not be ruled out.

Adult↗
PubMed1982

Drug monitoring of surgical patients.

Intensive drug monitoring of surgical patients was carried out on selected wards in five hospitals in the United States, Scotland, and New Zealand from 1977 through 1981. This report describes the methods and some findings from the monitoring of 5,232 such patients. Patients received, on the average, nine drugs on the ward, and adverse reactions were associated with 2.2% of these drug orders. Of the 1,150 drug-attributed adverse reactions, only 62 were considered "major" by the attending physician, and 35 (affecting 20 patients) were termed "life threatening." There were no drug-attributed deaths.

Adolescent↗
PubMed1982

Nonestrogenic drugs and breast cancer.

The relation between breast cancer and selected nonestrogenic drugs was evaluated in the Group Health Cooperative of Puget Sound, Seattle, Washington, a prepaid health care organization with computerized information on diagnoses and outpatient drug use. No important positive associations with breast cancer were found in a follow-up study of 302 women aged 35-74 years. These women were newly diagnosed with breast cancer in 1977-1980 and were studied in relation to exposure in the six months prior to diagnosis to one or more of the following drugs: diazepam, digitalis glycosides, medroxyprogesterone acetate, methyldopa, metronidazole, phenothiazines, tricyclic antidepressants, thiazides, thyroid/levothyroxine sodium, or spironolactone. A modest association between recent reserpine use and breast cancer was present (risk ratio = 1.7, 90% confidence interval 0.9-3.3).

Adult↗