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Biomedical subjects

D A Feeney

Publications and source records attributed to D A Feeney.

At least 55 records · Page 3Linked to original sources

Two-dimensional, gray-scale abdominal ultrasonography. General interpretation and abdominal masses.

The techniques of and general interpretive principles of gray-scale, two-dimensional abdominal ultrasonography in small animals are described. Using case examples, commonly encountered imaging artifacts and categories of disease are integrated with a description of what was obtained by radiography. Tissue echogenicity as a basis for general assessment of organ abnormalities as well as the expectations (interpretive and prognostic) one should have of abdominal ultrasonography are presented.

Abdomen↗

Effects of intravesical hydrostatic pressure and volume on the distensibility of the canine prostatic portion of the urethra.

Positive-contrast retrograde urethrocystograms were obtained serially on 12 male dogs weighing 11.4 to 23.2 kg before, during, and after the injection of contrast medium until the urinary bladder neck and prostatic and membranous portions of the urethra remained open and distended as viewed by fluoroscopy. Correlations of intravesical volumes and pressures required to achieve maximum distension of the midprostatic portion of the urethra with body weight and surface area were not significant. Because of the variability in intravesical volumes and pressures encountered at maximum distension of the prostatic portion of the urethra, a dose of contrast material expressed relative to body weight or surface area could not be determined for consistently providing maximum distension of the prostatic portion of the urethra.

Animals↗

Postoperative complication of cervical fracture repair in a dog.

Fracture and luxation of the second cervical vertebra of a dog were repaired with braided polyester sutures. After 28 months, the dog became ataxic. Compression of the spinal cord at C1-2 was seen on a myelogram. Surgical exploration of the area revealed a granuloma associated with the sutures and compressing the spinal cord. After the granuloma was removed, the dog recovered and has remained neurologically normal for 21 months. The abnormal tissue was determined histologically to be a pyogranuloma.

Animals↗

Thoracic wall and pulmonary trauma in dogs sustaining fractures as a result of motor vehicle accidents.

The records of 267 dogs seen at the University of Minnesota Veterinary Teaching Hospital for fractures resulting from motor vehicle accidents were examined to determine the prevalence and types of thoracic wall and pulmonary trauma associated with such cases. Results were analyzed for type and prevalence of thoracic wall and pulmonary injury, and for the prevalence of such injury in dogs with and without extrathoracic injury, in dogs with fractures of single vs multiple bones, in dogs with single fractures of specific bones, in dogs with fractures in the cranial vs the caudal one half of the body, and in dogs with fractures ipsilateral vs contralateral to thoracic injury. The overall prevalence of thoracic wall and pulmonary trauma was 38.9%; pulmonary contusions, pneumothorax, and fractured ribs were the most common injuries. More than 1 type of thoracic wall or pulmonary injury was diagnosed in 57.7% of the cases. Of the dogs with thoracic injury, 24% also had extrathoracic injuries; 16.5% of dogs without thoracic injury had extrathoracic injuries, not including fractures. Of the dogs with fractures of 1 bone, 36.3% had thoracic injuries. Of the dogs with fractures of more than 1 bone, 42.3% had thoracic injuries. The prevalence of thoracic wall and pulmonary trauma was significantly associated with the site of the fracture (cranial vs caudal and ipsilateral vs contralateral); significant association with the specific bone fractured was also seen for some fractures.

Accidents, Traffic↗

Radiographic appearance of pulmonary metastases from transitional cell carcinoma of the bladder and urethra of the dog.

Eleven cases of histologically proven transitional cell carcinoma of the bladder or urethra of the dog were selected for evaluation and characterization of the varied radiographic appearances of the lungs. In the 8 dogs with metastases, those appearances included radiographically normal pulmonary parenchyma, a semidense, diffuse, lacelike haze referred to as interstitial opacity, nodular interstitial opacity, and consolidations. One affected dog had hilar lymphadenopathy. In the 3 dogs without pulmonary metastases, the radiographic appearance was either normal pulmonary parenchyma or increased unstructured interstitial opacity. Of all dogs in the study, 6 had a radiographic appearance of increased unstructured interstitial opacity. Four of those 6 had histologically proven metastases in the peribronchiolar lymphatics or alveolar capillaries. Dyspnea was not identified in any of the affected dogs. The radiographic appearance for 3 of the 8 dogs with pulmonary metastases was misinterpreted as opacity compatible with age. The radiographic appearance for 1 of the 3 dogs without pulmonary metastases was misinterpreted as highly suspect for metastases.

Animals↗

Two-dimensional, gray-scale ultrasonography for assessment of hepatic and splenic neoplasia in the dog and cat.

An analysis was made of 17 cases of microscopically proven hepatic and splenic neoplasms, with the objective of describing the ultrasonographic findings and determining how interpretation of these findings contributed to the diagnosis and prognosis of these cases. The ultrasonographic appearance of these tumors ranged from focal, large (6 to 20 cm diameter) mixed hyperechoic/hypoechoic masses to multifocal (0.5 to 2.0 cm diameter) hypoechoic masses. The ultrasonographic appearance was not specific for the microscopic cell-type of the neoplasm. When the combined clinical, hematologic, serum chemical, and ultrasonographic findings were interpreted, neoplasia was always the primary consideration, but microscopic confirmation was mandatory. The uses of ultrasonography in these cases were: (1) to characterize the internal architecture of a mass identified radiographically, (2) to confirm the organ of origin of the mass, (3) to define the extent of disease in or around an affected organ, (4) to evaluate palpable abdominal mass(es) in the presence of poor abdominal radiographic contrast, and (5) to identify previously undetected or unsuspected metastases. Three interpretive errors were found, but only one would have influenced the prognosis for that specific patient.

Animals↗

Low anterior anastomotic dehiscence following preoperative irradiation with 6000 rads.

Twenty mongrel dogs received 6000 rads of irradiation to the rectum and colon using the Nominal Standard Dosage Equation. Three weeks after irradiation each dog underwent anterior resection of the rectosigmoid with reconstruction randomized to either an EEA stapled or a two layer handsewn anastomosis. Each dog was studied digitally and by barium enema at the time of surgery, on the seventh postoperative day, and at autopsy. Five clinically significant leaks and three radiographic leaks occurred in the EEA stapled anastomoses. The handsewn anastomoses had five clinically significant leaks and two radiographic leaks. The data indicate that low anterior resection with either an EEA stapled or handsewn anastomosis cannot be done safely after 6000 rad preoperative irradiation.

Animals↗

Effects of sterilized micropulverized barium sulfate suspension and meglumine iothalamate solution on the genitourinary tract of healthy male dogs after retrograde urethrocystography.

A sufficient quantity of 30% w/v sterile barium sulfate suspension was infused into the caudal portions of urinary tracts of 12 young adult healthy male Beagles to induce vesicoureteral reflux. A control group of dogs was infused with a 7.5% solution of meglumine iothalamate. The dogs were radiographed at 1, 6, 13, and 29 days later. Three dogs from each group were euthanatized and necropsied (1 each) after radiography at each of these times. In some dogs, radiopacity in the prostate, urinary bladder, and renal pelvic diverticula due to barium persisted throughout the 30-day observation period. Opacity at or beyond 24 hours was not found in dogs infused with iothalamate. Light microscopy revealed barium either free or within macrophages in the submucosa of the bladder, in glandular and stromal areas of the prostate, and in the kidney. Renal barium was limited to pelvic diverticula (3 dogs), in a medullary tubule (1 dog), and in cortical tubules (2 dogs). Significant lesions attributable to barium were not seen in kidneys of dogs in the barium group. Iothalamate induced focal to multifocal inflammatory responses in some prostates; barium was phagocytosed by macrophages. Focal transient inflammatory and ulcerative lesions induced by bladder distention were observed in the bladder and urethral mucosa in both groups.

Animals↗

Dyschondroplasias, including osteochondrosis, in boars between 25 and 169 days of age: radiologic changes.

Boars in 6 different groups (between 25 and 169 days of age) were examined radiographically to determine the age of onset of lesions associated with the sites of endochondral ossification in limb bones. Although lesions were in histopathologic sections of physes from all groups of pigs, they were not found frequently in radiographs of live animals until boars were more than 100 days old. Microscopic lesions were infrequent in articular-epiphyseal (A-E) complexes of pigs less than 80 days old, and radiographic examination of live animals had limited value until animals were greater than 100 days old. Radiographs of slabs of bone were useful in the detection of physes with lesions in all age groups and A-E complexes with lesions in boars 100 days of age or older. So that the accuracy of radiographic examination of live animals for the diagnosis of dyschondroplasias could be evaluated, a comparison was made between the numbers of growth cartilages with lesions as determined by radiologic examination of live animals, radiographic examination of slabs of bone, and light microscopy (examination of tissue sections). Only 21% of the lesions associated with physes and 22% of the lesions associated with A-E complexes were detected in radiographs of bones of live pigs. The authors concluded that the latter method was inaccurate for the identification of dyschondroplastic foci. Identification of lesions by examination of radiographs of slabs of bone was only slightly more accurate, since 33% of physes and 23% of A-E complexes which had lesions were found. Potential errors in evaluation of radiographs were discussed.(ABSTRACT TRUNCATED AT 250 WORDS)

Aging↗

Maximum-distention retrograde urethrocystography in healthy male dogs: occurrence and radiographic appearance of urethroprostatic reflux.

Urethroprostatic reflux was found during retrograde urethrocystography in 21 of 24 mature healthy Beagles. Minimal parenchymal-positive contrast " blushes " near the urethra were identified, but no massive accumulations of contrast medium within the prostate were found. A particulate contrast medium, sterilized barium sulfate, was used in 12 of the dogs. After retrograde urethrocystography, the barium particles were found in the secretory (acinar) portion of the prostatic parenchyma, confirming that urethroprostatic reflux extended beyond the prostatic duct system that directly empties into the urethral lumen.

Animals↗

Maximum-distention retrograde urethrocystography in healthy male dogs: occurrence of vesicoureteral reflux.

Twenty-four healthy, mature male Beagles were examined radiographically for vesicoureteral reflux (VUR) by maximum-distention retrograde urethrocystography. Bilateral VUR was observed in 9 dogs and unilateral VUR was observed in 3 dogs. The VUR occurred when the bladder was full or nearly full when maximum bladder filling was defined by trigonal-prostatic urethral dilation. The refluxed contrast medium reached the renal pelves in all but 3 of the 21 affected ureters.

Animals↗

Vesicoureteral reflux induced by manual compression of the urinary bladder of dogs and cats.

Vesicoureteral reflux caused by manual compression of the urinary bladder performed to obtain urine samples was evaluated by contrast radiography in 10 sedated, clinically normal male and female dogs and in 10 sedated, clinically normal male and female cats. Vesicoureteral reflux occurred in 50% of the dogs and in 40% of the cats. Application of digital pressure to the urinary bladder for a prolonged period to initiate urine voiding was associated with a greater occurrence of reflux than was application of digital pressure for a transient period. Contrast material refluxed into the prostate gland of 3 of 6 male dogs.

Animals↗

Orthovoltage radiation of normal canine nasal passages: assessment of depth dose.

Frozen heads of 9 clinically normal dogs were irradiated with orthovoltage x-rays. Surface doses and nasal cavity depth doses were measured, and the percentage of surface dose (depth dose) was calculated at random depths from the dorsal cutaneous surface in transverse planes through the medial and lateral canthi. Depth dose of 2 orthovoltage x-ray beams having half-value layers of 1.5 mm of Cu (96 keV) and 2.6 mm of Cu (134 keV) were compared with and found to resemble that reported in depth dose tables based on soft tissue equivalent material. Any differences (identified graphically) in depth dose, compared with that described using a uniform (soft tissue equivalent) phantom, were explained by the variations in tissue composition and the presence of air within the normal nasal and paranasal cavities.

Animals↗

Malignant neoplasia of canine ribs: clinical, radiographic, and pathologic findings.

An analysis was made of 17 cases of microscopically proven rib neoplasms, with the objective of evaluating the variability of clinical and radiographic findings, the neoplastic cell types, the occurrence of metastases, and the survival time following the diagnosis. In 15 dogs with primary rib neoplasms and in 2 dogs with secondary (presumably metastatic) rib neoplasms, the clinical signs commonly included dyspnea and a localized swelling on the thoracic wall. For the dogs with primary rib neoplasms, the mean age was 4.5 years, with a range of 1.3 to 16 years. On radiography, rib osteolysis, extra and/or intrathoracic soft tissue masses often containing areas of mineralization, and pleural effusion were commonly identified. Ribs 5 through 9 were the most commonly affected and the right side was involved twice as often as the left side. Osteosarcoma was the most frequently diagnosed tumor, but chondrosarcomas and hemangiosarcoma were also found. At necropsy, over 50% of the dogs with primary rib neoplasms had metastases in the lungs. Less than 10% of the dogs with primary rib osteosarcomas survived more than 4 months after the diagnosis.

Animals↗