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Biomedical subjects

D A Franklin

Publications and source records attributed to D A Franklin.

7 recordsLinked to original sources
PubMed1976

A computer-based technique for measurement of renal parenchymal area on intravenous urograms.

Accurate measurement of the renal parenchymal area of intravenous urograms is discribed using a graphic tablet with a pressure-sensitive surfact linked on-line to a computer. The area outlined on the tablet is immediately computed and shown in square centimetres on a television screen and on a data print-out. The renal areas of 22 patients' urograms were studied before the three months after renal stone removal under local hypothermia. Renal function was measured by creatinine clearance. Conventional measurements of renal length, width and area were also performed for comparison. Results confirmed that while overall kidney size was reduced following operation, the parenchymal area and creatinine clearance were unaltered. This computer-based technique is simple to perform, quick and accurate, and provides quantitative information on intravenous urograms.

Anthropometry↗
PubMed1975

A computer-based record and organisation system for a department of urology.

This paper describes the development and practical application of a computer-based record system in a urological department. It demonstrates how such a system can provide a clinical flow sheet for day-to-day use combined with a computerised data store for both clinical evaluation and for research purposes. The paper also outlines how the system has improved patient handling and general departmental efficiency.

Appointments and Schedules↗
PubMed1975

A study of practolol elimination in all grades of chronic renal failure.

Plasma and renal elimination of practolol have been studied in 12 patients with varying degrees of stable chronic renal failure and 14 normal volunteers. Each individual received 200 mg of oral practolol. The mean time to peak plasma level in the group of patients with renal failure was later than in the normal group, the difference between the two being significant. There were significant correlations between plasma practolol clearance and creatinine clearance, and also between renal practolol clearance and creatinine clearance. Total clearance of practolol from plasma was slightly higher than its renal clearance, the difference being significant, which suggested a small non-renal component to elimination. Renal practolol clearances tended to exceed creatinine clearances, the difference being significant, suggesting some renal tubular secretion of the drug. It is suggested that--in patients with chronic renal failure--the maintenance dose of practolol be reduced roughly in proportion to the reduction in creatinine clearance from normal. If effective plasma practolol concentrations are required quickly, the need for giving a loading dose becomes important under such circumstances.

Adult↗