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Biomedical subjects

D A Garber

Publications and source records attributed to D A Garber.

16 recordsLinked to original sources
PubMed1992

Gene transfer into mammalian central nervous system using herpes virus vectors: extended expression of bacterial lacZ in neurons using the neuron-specific enolase promoter.

A herpes simplex virus (HSV) vector in which the mammalian promoter for neuron-specific enolase (NSE) controls expression of a marker gene was analyzed for its ability to drive expression of this foreign gene in culture and in vivo. In cultured cells, the vector appeared to give neuron-specific expression. Introduction of 10(6) pfu of the virus into the adult rat caudate nucleus by stereotactic injection was not toxic to the animals and yielded beta-galactosidase (beta-gal)-positive neurons for at least 30 days after viral inoculation. This recombinant herpes virus vector is the first described to use a mammalian promoter to yield extended expression of a foreign gene product in the adult mammalian central nervous system (CNS).

Animals↗
PubMed1992

Patient maintenance of esthetic restorations.

There are probably as many ways to maintain esthetic restorations as there are restorations. After esthetic treatment is completed, schedule a mandatory postoperative appointment to make certain that whatever technique the patient uses is effective. At the postoperative visit, it should be apparent that the patient's tissue is healthy. If the tissue has not healed, some change in home care or additional periodontal or restorative treatment may be necessary. There are virtually hundreds, perhaps even thousands of home plaque removal devices. The ones mentioned here have worked for us and are therefore discussed. It isn't the type of device that is critical, however, but patient compliance. The described regimens have worked effectively for us in overcoming this obstacle of compliance. Appropriate recall visits with the hygienist should be made at one- to six-month intervals. In the final analysis, your success with esthetic restorations may well depend on your patients' success with esthetic maintenance.

Dental Devices, Home Care↗
PubMed1989

Direct composite veneers versus etched porcelain laminate veneers.

It would appear that over the years, the inherent weakness in composite veneering has been the composite itself. The etched porcelain restoration offers the advantages of increased strength, color, stability, and biocompatibility for a veneering material using composite merely as a luting agent. With the ongoing development of porcelain material, it is possible that the etched porcelain restoration will all but replace direct bonding in most clinical situations.

Acid Etching, Dental↗
PubMed1979

Loss of arch integrity due to interproximal caries.

A simple orthodontic procedure, utilising a fixed appliance, is described. The procedure is adopted to correct a problem commonly met with in conservative dentistry. It enables a correctly contoured restoration to be placed which will prevent the development of further dental problems.

Dental Caries↗
PubMed1979

A temporary-permanent splint.

A method of temporary permanent splinting has been presented which enables the clinician to stabilize anterior teeth aesthetically and rigidly without resorting to cast restorations. The method utilizes an acid-etch composite technique with T.M.S. Pins and has shown itself to be a rapid, cosmetic and durable alternative to either the temporary intra-coronal wire ligation or the more permanent gold prosthesis.

Acid Etching, Dental↗
PubMed1977

Adjunctive orthodontics in oral rehabilitation.

This paper encompasses a few of the more common indications for adjunctive orthodontics. It is by no means a complete list, but relates to those problems often seen in restorative practice and readily handled by the trained restorative clinician. A multitude of techniques exist for the accomplishment of any of the objectives discussed above. The choice of method to be utilized lies with the aptitude of the clinician concerned. It should be noted that, irrespective of the method used, some form of stabilization will be essential on completion of the tooth movement.

Dental Occlusion↗