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Biomedical subjects

D A Ginsburg

Publications and source records attributed to D A Ginsburg.

9 recordsLinked to original sources

Selecting an automated patient accounting system.

Hospitals are now considering replacing their present patient accounting systems. But to do so, many issues and questions must be raised, including, how to evaluate a new system and when to replace an existing one. When considering a new financial system, a checklist addressing the hospital's own requirements, conditions, and objectives can be a helpful guide. In fact, development of such a checklist should be considered a major part of the planning process, forcing the hospital to consider all its needs and requirements apart from a specific vendor's system.

Accounting↗

Selecting automated patient care systems.

Although the nursing department may contribute to the selection process for other automated hospital systems, the nursing administrator's most critical and complex project will be selecting the patient care system. This article provides an overview of the key issues that must be examined in the selection process for a patient care system.

Administrative Personnel↗

The prenatal prediction of thrombocytopenia in infants of mothers with clinically diagnosed immune thrombocytopenia.

The management of the pregnant patient with immune thrombocytopenia is complicated by the unavailability of the fetal platelet count. Since the transplacental passage of antiplatelet antibodies mediates infant thrombocytopenia, measurement of maternal platelet-associated IgG might predict infant outcome. We related the maternal platelet count and platelet-associated IgG level to the infant's platelet count in 41 pregnancies in 38 patients who were clinically diagnosed as having immune thrombocytopenia. Fifteen of 39 live-born infants were thrombocytopenic at delivery. Maternal platelet-associated IgG was predictive of infant platelet count but maternal platelet count was not; only one of the 20 infants delivered of the 18 thrombocytopenic mothers with normal platelet-associated IgG was affected, whereas 11 of 12 thrombocytopenic mothers with elevated platelet-associated IgG had thrombocytopenic infants. Five infants died in utero between 18 and 28 weeks' gestation, but otherwise there was no significant morbidity in the live births. Measurement of platelet associated IgG in mothers with immune thrombocytopenia during pregnancy can be used to predict infant thrombocytopenia, although it does not predict the severity of the thrombocytopenia.

Adult↗

Types of hypoxic and posthypoxic delta activity in animals and man.

1. Two types of hypoxic delta activity were observed in ECoG records of dogs subjected to exsanguination, sudden cardiac arrest resulting from ventricular fibrillation or mechanical asphyxiation, as well as during post-hypoxic recovery. They were polymorphous delta activity (PDA) and "standard slow complexes" (SSCs). 2. These two types of delta activity were found to differ from each other as to the shape of the potentials; their amplitude in monopolar and bipolar leads; the cortical areas in which the activity exhibited the highest amplitude; the degree of manifestation in the cortex and subcortical structures; their relation to activating influences; their dependence on the stage and character of hypoxia. 3. Analysis of EEG records of patients during and after hypoxia made it possible to distinguish both PDA and a type of delta activity similar to the SSCs observed in experimental animals. 4. It is suggested that the appearance of SSCs is determined by the activity of a pacemaker situated in the diencephalon and responding to pO2 changes, and that the mechanism of SSC generation is closer to that of monorhythmic, bilataerally synchronous delta waves observed in primary irritative or epileptogenic processes in the diencephalon.

Animals↗

Correlation analysis of delta activity generated in cerebral hypoxia.

1. Differences in spatial and temporal characteristics between polymorphous delta activity (PDA) and "standard slow complexes" (SSCS) resulting from grave cerebral hypoxia have been demonstrated by means of digital correlation analysis and on line recording of correlograms. 2. PDA observed in the human EEG and the ECoG of dogs is characterized by the absence of periodic organization (high extinction indices of auto- and crosscorrelation functions) and absence of spatial synchronization when recorded from widely separated areas of the hemispheres (low correlation coefficients, significant and variable time shifts), with bilateral symmetry of slow waves being preserved. 3. Delta waves recorded from nucleus amygdalae, nucleus caudatus, thalamus, hypothalamus and midbrain in the dog differ from cortical PDA by a more synchronous and rhythmically arranged process. 4. During the establishment of SSC activity correlograms show a synchronous process common to all cortical aand subcortical areas characteized by very high values of correlation coefficients. 5. It is suggested that the unorganized slow wave PDA process could arise under conditions of hypoxic dysfunction of distant cortico-cortical relationships, accompanied by weak subcortical pacemaker influences. The process reflects local coexcitation of relatively limited cortical areas. The particular statistical characteristics of SSCs generated during further increase in oxygen deficit can be accounted for by simultaneous generation of responses in some subcortical areas to single volleys of impulses from a hypothetical pacemaker, accompanied by a passive wave propagation towards a cortex completetly depressed by hypoxia

Adolescent↗