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Biomedical subjects

D A Hansen

Publications and source records attributed to D A Hansen.

31 records · Page 2Linked to original sources

Effect of alprenolol on mortality among patients with definite or suspected acute myocardial infarction. Preliminary results.

A double-blind study of alprenolol versus placebo was done in patients with definite or suspected myocardial infarction to show the effect of the drug on mortality-rate after a year of treatment in patients aged less than or equal to 65 and to study the tolerance of the drug by patients greater than 65 years of age. The dose given was 5--10 mg intravenously, followed by 200 mg twice a day, orally. Patients in whom beta-blockade was contraindicated were excluded. All deaths, side-effects, and dropouts were recorded. Of the 480 patients in the study, 238 patients received alprenolol and 242 placebo. During the year of follow-up 108 patients dropped out from the study. Mortality was not reduced in patients greater than 65 years of age. In those less than or equal to 65 years alprenolol significantly reduced mortality-rate (20% mortality in placebo group vs 9% in treated group). There was also a significant reduction in mortality-rate among those with definite infarction (28% in the placebo vs 15% in the treated group).

Acute Disease↗

Angiofollicular lymph node hyperplasia.

One case of angiofollicular lymph node hyperplasia simulating a salivary gland tumour is presented. In a review of the literature containing some 220 cases, 29 cases in the neck were found. A survey of these 29 cases is given, and another two cases of special oto-rhino-laryngologic interest are mentioned. Furthermore, a description of the tumour and a brief discussion of aetiology and differential diagnosis are given.

Diagnosis, Differential↗

beta-Cyclodextrin as an aid to peritoneal dialysis. Renal toxicity of beta-cyclodextrin in the rat.

A peritoneal dialysate containing beta-cyclodextrin has been shown to accelerate the removal of intravenously administered phenobarbital in rats. It was found that high concentrations of beta-cyclodextrin were toxic to the animals in the single exchange technique employed. The renal toxicity was estimated by measuring blood urea nitrogen values in the rats following oral and intraperitoneal administration of the cyclic amylose.

Amylose↗

A study of the influence during trituration of air-borne impurities on the strength of amalgam.

The purpose of this study was to determined the effect of air-borne gaseous impurities, introduced during trituration, on the strength of amalgams. Four experiments were conducted. Each experiment consisted of a control group (1) in which the amalgam was triturated in air and an experimental group (2) in which the amalgam was triturated in argon, an inert gas. Standard specimens yielded mean diametral tensile strengths of 5950 psi (1) and 6603 psi (2). Hand compacted specimens yielded mean diametral tensile strengths of 5829 psi (1) and 6412 psi (2). Standard specimens yielded mean compacted hydraulically yielded mean uniaxial tensile strengths of 10,928 psi (1) and 11,660 psi (2). Statistically, the differences between the means for each experiment are significant. Hence, trituration in an inert gas has been shown to be an effective method for increasing the strength of amalgam.

Air Pollution↗

Torticollis.

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Adolescent↗

Cancrum oris.

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Anesthesia, General↗