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D A Labianca

Publications and source records attributed to D A Labianca.

6 recordsLinked to original sources

Statistical analysis of blood- to breath-alcohol ratio data in the logarithm-transformed and non-transformed modes.

The statistical analysis of non-transformed and logarithm-transformed blood- to breath-alcohol ratios ("blood/breath ratios") is detailed. The data analyzed were derived from 137 simultaneous blood-alcohol and breath-alcohol concentration measurements made between 15 and 179 min after the end of drinking, with 136 of the measurements obtained during the 15- to 124-min time frame. Although the distribution of the non-transformed ratios is positively skewed, and that of the logarithm-transformed data more closely approximates the normal distribution upon visual inspection, both analyses generated results that do not differ significantly from each other when considered in the context of "mean ratios + or - 2SD". This is in accord with the results of the Kolmogorov-Smirnov goodness-of-fit test, which does not reject either dataset and demonstrates that both are approximately normal. Since the logarithm-transformed data generate more conservative statistical blood/breath ratio ranges than the non-transformed data, they were selected as the basis for the principal conclusion of this work. That conclusion is a refutation of the argument that, breath-alcohol analyzers relying on a 2100:1 blood/breath ratio tend to underestimate the blood-alcohol concentrations of driving-while-intoxicated arrestees because the commonly accepted mean postabsorptive ratio is 2300:1. In fact, whenever the absorption status of a driving-while-intoxicated arrestee at the time of a breath test cannot be definitively established, the results of this work support the application of a relative error range of -40% to +28% for 95% of the population, based on a statistical blood/breath ratio range of 1259:1 to 2679:1, and -46% to +42% for 99% of the population, based on a statistical range of 1128:1 to 2989:1.

Absorption↗

Analysis of breath alcohol via infrared spectrophotometry: predicting false ethanol results by application of the base-line method to vapor phase infrared spectra.

Toluene and a mixture of the isomeric xylenes are common organic solvents that have been implicated in false ethanol results produced by older models of the Intoxilyzer 5000, a breath alcohol analyzer that uses infrared spectrophotometry to quantitate ethanol in breath samples. A straightforward method is described which predicts this type of interference in analyses conducted on such models. The methodology relies on a comparison of the vapor phase infrared spectra of toluene and xylene with the corresponding spectrum of ethanol, using the base-line method to estimate relative absorbances at the two analytical wavelengths employed by the Intoxilyzer 5000. The point is also made that, given the potential for such interference, a model of the Intoxilyzer 5000 has been developed that has the capability to compensate for this problem.

Breath Tests↗

Medicolegal alcohol determination: variability of the blood- to breath-alcohol ratio and its effect on reported breath-alcohol concentrations.

There is substantial agreement among scientists that the variability of a person's blood- to breath-alcohol ratio contributes significantly to the experimental error in results from breath-alcohol analysis. Some have argued that the need to correct for this source of error can be eliminated by reporting breath test results in units of breath-alcohol concentration rather than blood-alcohol concentration. A simple mathematical proof is presented to demonstrate that this is not the case. Moreover, the scientific and legal flaws of this argument are discussed, and recommendations are offered for dealing with the problems that have developed from adoption of this view.

Alcoholism↗