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Biomedical subjects

D A Pyke

Publications and source records attributed to D A Pyke.

At least 109 records · Page 6Linked to original sources

Medical English for Finnish doctors.

Courses in medical editing and medical English are relatively new and infrequent. We have now provided seven of them for Finnish doctors who wished to publish their work in English, to present papers in English to conferences, to work in English-speaking countries-or who wanted to improve their knowledge of the language. Although such courses should be tailored to individual needs, most participants seem to have found them helpful, particularly the sessions spent in the language laboratories. We suggest that courses in medical English might be useful for both medical students and postgraduate doctors outside English-speaking countries.

England↗

Effect of carbohydrate restriction in obese diabetics: relationship of control to weight loss.

Two hundred newly diagnosed, fat diabetics were studied to determine whether control of the diabetes depended on loss of weight or on carbohydrate restriction alone. Satisfactory control was achieved by dietary treatment alone in 159 patients 30 required oral hypoglycaemic drugs and 11 were 18 of whom had actually gained weight. Of the remaining patients, 30 required oral hypoglycaemic drugs and 11 were still uncontrolled but not yet on other treatment.The mean initial excess weight of all 200 patients was 28%. Of those who remained uncontrolled on diet alone the mean initial excess weight (31%) was slightly but not significantly greater than that of those who were controlled (27%). Patients who were controlled lost slightly more weight than patients who were not, but their excess weight at the time of control was still 21%.We conclude that in 80% of obese diabetics control can be achieved by diet alone and that it is usually independent of weight loss.

Adult↗

Diabetes in twins.

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Diabetes Mellitus↗

Glucose tolerance and serum insulin in identical twins of diabetics.

Glucose tolerance with serum insulin assay has been carried out in 24 apparently unaffected identical twins of diabetics. Glucose values were significantly higher and insulin values significantly lower than in control subjects, but there was considerable individual variation and in half the cases glucose tolerance was normal. There was no case of increased insulin response. In these twins glucose tolerance and insulin response were not correlated with weight, family history of diabetes, age at diagnosis of diabetes in the affected twin, time since that diagnosis, nor with age at testing the unaffected twin. On retesting 12 of the twins after two years no significant differences were found from the first testing.We conclude that not all these twins are likely to develop diabetes, that the assumption that identical twins of diabetics are necessarily "prediabetic" is probably erroneous, and that factors other than genetic ones are important in the aetiology of diabetes.

Adolescent↗