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Biomedical subjects

D A Stringer

Publications and source records attributed to D A Stringer.

83 records · Page 5Linked to original sources

Radiologic manifestations of malabsorption: a nonspecific finding.

Children demonstrating a radiologic malabsorption pattern on small bowel follow-through study performed for other reasons are frequently subjected to intensive gastrointestinal investigations, even in the absence of clinical manifestations of malabsorption. To determine the usefulness of this radiologic finding, the clinical findings of all patients with the typical malabsorption pattern on small bowel follow-through examination were reviewed retrospectively. The presence of a malabsorption pattern was based on three radiologic criteria: flocculation and segmentation of barium, thickening of mucosal folds, and dilation of intestinal loops. Thirteen patients fulfilled the criteria for radiologic malabsorption pattern, but six (46%) had no clinical evidence of malabsorption, according to 3- to 5-day fecal fat analysis. In addition, five of these patients had normal mucosal histologic findings on duodenal biopsy. It was concluded that radiologic malabsorption pattern is a nonspecific finding, and in the absence of other clinical features suggestive of malabsorption or growth failure further investigations may not be justified.

Barium Sulfate↗

CT manifestations of Menkes' kinky hair syndrome (trichopoliodystrophy).

A patient with Menkes' syndrome is reported. This patient has survived to the age of six years without mental retardation, and shows previously unreported computed tomographic (CT) findings of tortuous vessels and unusual osseous manifestations of undertubulation of long bones and posterior vertebral body scalloping.

Bone and Bones↗

Pathophysiology of the ciliary motility syndromes.

The ciliary motility syndromes are characterised by specific and genetically determined defects of cilia with resulting impairment of mucociliary defense mechanisms in the respiratory tract. The ciliary pathobiology, clinical observations, serial pulmonary function and chest radiographs are reviewed and correlated for a series of 33 patients with the ciliary motility syndromes, aged from 0.5 to 75 years. The clinical course and progressive nature of this disease emphasizes the importance of early and accurate diagnosis to prevent irreversible pulmonary damage.

Adolescent↗

The use of the right decubitus position in computed tomography of the liver and pancreas.

Sixty patients underwent computed tomography (CT) with a 20 s scanner of the upper abdomen in the supine and right decubitus positions. The images of the liver were compared. The scores for the hepatic image were better when the patient was in the right decubitus position. The scores for the image of the pancreatic head were about the same in the two positions but improvement occurred in the right decubitus position in nearly half the patients. Scores for the other parts of the pancreas and for the pancreas as a whole were usually worse when in the right decubitus position although improvement did sometimes occur. Scanning in the right decubitus position has been demonstrated to be of value in reducing artefact shadows in the hepatic image and may on occasions improve the quality of the pancreatic image. Accordingly scanning in the right decubitus position is a useful aid when supine views have given poor results or when the presence of a lesion is equivocal.

Humans↗

Juvenile hyaline fibromatosis.

A case of juvenile hyaline fibromatosis in a ten-year-old Asian girl is presented. This autosomal recessively inherited condition has not previously been described in the radiological literature. This patient demonstrates well the characteristic radiological appearance. The literature of juvenile hyaline fibromatosis and of the other generalized fibromatoses is reviewed and the interrelationship is discussed.

Child↗

The value of computed tomography in the early assessment of comminuted fractures of the calcaneus: a review of three patients.

Computed tomography (CT) was performed within 4-8 days of injury in three patients with five fractures of the calcaneus. Three of the fractures were comminuted, and CT gave graphic additional information to the plain radiographs. Three fractures were undisplaced and were managed conservatively. In the other two, there was displacement of bony fragments, and these were treated operatively. In these, CT gave valuable preoperative information regarding the size and location of fracture fragments and helped the surgeon determine the site of incision and type of surgery required. The CT findings were confirmed at operation. CT therefore provides useful information for the management of these difficult fractures.

Adolescent↗

Functional duodenal obstruction (superior mesenteric artery or cast syndrome) in cerebral palsy.

An 8-yr-old girl with cerebral palsy who was chronically malnourished presented with functional duodenal obstruction (superior mesenteric artery or cast syndrome) proven by barium meal. Six months of feeding through a fluoroscopically positioned gastrojejunal tube generated sufficient weight gain and increase in body bulk to cure the functional obstruction.

Cerebral Palsy↗