Rifampicin-dependent antibodies in twice-weekly treated patients.
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Biomedical subjects
Publications and source records attributed to D Alexandrescu.
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A whole rural population of 16359 subjects was followed for a period of 24 years. This period of 24 years is well divided from the viewpoint of the succesive systematic detection three intervals being selected, as follows: a) the stage of usual anti-tuberculous assistance; b) the stage of scientific experimentation consisting in 3 radiophotographic detections repeated every two years and the annual control of groups with high risk, between 1960--1965, completed by integral biological detection in children (every year) and bacteriological controls. The population controls were followed by the diagnosis; c) the stage of discontinuing the experiment when current antituberculous assistance was resumed, between 1966 and 1974. All cases of active pulmonary tuberculosis, that have been recorded through all the methods of investigation over a period of 24 years in all these localities are correlated, on the one hand to one another, and on the other hand with objective documents obtained during the period of intensive control of the population over the 6-years interval. Thus the limits appear more correctly, within which this natural history of the disease can be detected through various types of population control, as well as some practical consequences for the improvement of the technique and of the control methodology in the future.
The county polyclinic provides the radiophotographic control of a rural population of 122.741 inhabitants from the area surrounding the capital city of Bucharest. Of the total number of cases of pulmonary tuberculoses that have been recorded only 16,6% were detected in the fixed center and 61,8% by integral detections, carried out by the radiophotographic caravans. That is why the authors consider that this is not the right time to abandon integral detection. The fixed centers, by performing examinations in all those entering new jobs detect cases of tuberculosis belonging to other geographical areas. Thus, of 235 cases detected over a period of 3 years, 67% belonged to other territories and only 33% were from the population normally covered by the center. This is the filter role played by fixed centers carrying out radiophotographic detection. As compared with the 235 cases of tuberculosis there were 399 cases of non-tuberculous pulmonary diseases.
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In the paper a systematic analysis is carried out of postoperative complications of colon surgery, 118 patients had complications, out of a total of 400 interventions on the colon. The complications are studied in relation with the time of their occurence and the localization of the neoplastic process, as well as from the point of view of the influence exerted by age and the "background" of the patients. A review is also made of the therapeutic attitudes required by the various complications, of the results obtained and finally a detailed analysis is presented of the causes that led to death of operated patients.
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The authors made use of maps prepared in the projection system known as the "Universal Transverse Mercator" (Gauss-Kruger projection) for the study of an epidemiometric indicator in tuberculosis, namely the instantaneous prevalence of bacili carriers on December 31 1978 in the Ilfov District. The representation allows to evaluate the density of sources of infection, and as a consequence, of areas in which antiepidemic measured have to be intensified. The extension of the study to other districts could provide data for assessing the epidemiologic potential in various territories, as well as comparisons and the dynamics of the potential. The method could also be used in the study of other epidemiometric indicators.
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