PubMed Health⌕ Search

Biomedical subjects

D Alonso Gutiérrez

Publications and source records attributed to D Alonso Gutiérrez.

9 recordsLinked to original sources

[Determination of insulin in saliva and its correlation with plasma insulin. Assessment of the possible participation++ of the salivary glands in the production of the hormone].

The finding of immunoreactive insulin (IRI) in saliva and an insulin-like protein, similar to pancreatic insulin and with the same biological activities, suggest that both products are pancreatic insulin stored and/or eliminated in the salival manner or an extrapancreatic hormone synthesis, bearing in mind the features which both glands share. The aim of this study is to ascertain whether the amount of insulin from saliva depends on plasmatic insulin and, if so, whether this is a form of elimination. Our results pointed out that the amount of insulin in saliva is similar to the plasmatic insulin in those patients with normal pancreatic function. The oral glucose tolerance test was carried out on 20 patients. The maximum insulin level was produced at the same time as maximum serum glucose level, taking place 60 minutes later. These data, support the concept that salival insulin is a product of the elimination more than synthesis by salival glands, however we can not exclude the possibility of synthesis by the salival gland without direct studies, the ideal test being the immunocytochemist.

C-Peptide↗

[Levels of lead, cadmium, zinc and arsenic in the water in the province of Salamanca. Multidepartmental coordinated project of investigation supported by the Junta of Castilla Leon in 1884].

BACKGROUND: To establish the degree of contamination by lead, cadmium, zinc and arsenic in the water in Salamanca province and its relationship with the provenance of the samples and their collection point. METHODS: Transverse, observational, descriptive epidemiological study. Province of Salamanca. RESULTS: Water from water pipes, fountains, springs, wells, rivers, streams and lakes in the province of Salamanca were studied, analyzing the lead, cadmium, zinc and arsenic contents of 180 samples using Atomic Absorption Spectroscopy. Results indicated that 56% of samples analyzed showed toxic levels of cadmium, and 28% of samples gave toxic levels of lead, but showed tolerable levels of zinc and arsenic. No major differences were observed in the degree of contamination by the four elements between the four provincial district areas. Levels of contamination by the four elements were compared for water from the water supply, and samples from wells, fountains, springs and surface water, showing similar contents of the elements studied. CONCLUSIONS: Findings suggest that the water in the province of Salamanca shows "naturally" high cadmium and lead content, probably due to the geological characteristics of the terrain.

Arsenic↗