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Biomedical subjects

D Angell

Publications and source records attributed to D Angell.

18 recordsLinked to original sources

Internal derangement of the temporomandibular joint: detection by single-photon emission computed tomography. Work in progress.

The diagnostic accuracy of both planar and single-photon emission computed tomography (SPECT) bone scintigraphy, radionuclide angiography, arthrography, and conventional radiography was evaluated in 36 patients with temporomandibular joint (TMJ) dysfunction undergoing preoperative testing. The sensitivity of SPECT bone scintigraphy (0.94) was comparable with arthrography (0.96) and significantly better than planar bone scintigraphy (0.76), radionuclide angiography (0.35), and transcranial lateral radiographs (0.04). While data for a larger asymptomatic control population are needed, preliminary results give SPECT a diagnostic specificity of 0.70 for internal derangements of the TMJ requiring surgical correction. It is concluded that SPECT bone scintigraphy is a useful noninvasive imaging test to screen for internal derangement of the TMJ.

Adolescent↗

Interference by inhibitors of the renin-angiotensin system with neurogenic vasoconstriction.

In the pithed rat preparation captopril, enalapril, teprotide and saralasin given intravenously attenuated pressor responses to both spinal sympathetic nerve stimulation and exogenous noradrenaline, indicating that angiotensin has a potent adrenergic facilitating action. Bi-lateral nephrectomy abolished the effects of captopril on nerve stimulation but responses to noradrenaline were still inhibited following nephrectomy, indicating that part of the post-junctional actions of captopril might not be angiotensin dependent. Both phenylephrine and clonidine are also inhibited by captopril in the pithed rat. It is thus not clear whether captopril is interacting with post-junctional alpha 1- or alpha 2-adrenoceptors. Vasoconstrictor responses to nerve stimulation are greater in SHR than WKY and captopril is more effective at inhibiting responses in the SHR than it is in WKY. These interactions between captopril and the sympathetic nervous system could explain the effectiveness of ACE inhibitors as antihypertensive agents.

Animals↗

Prevent and empower.

In an effort to short health care from ¿diagnose and treat¿ to ¿prevent and empower,¿ Henry Ford Health System (HFHS) launched the Center for Health Promotion and Disease Prevention, directed by Ronald M. Davis, MD, former chief medical officer of the Michigan Department of Public Health and former director of the Office on Smoking and Health at the US Centers for Disease Control and Prevention. He also headed up three Surgeon General's reports on smoking, including the 1988 report linking smoking to nicotine dependence.

Community Health Planning↗

Two are better than one.

On March 29, 1996, Marwan Abouljoud, MD, and Francisco Escobar III, MD, of Henry Ford Hospital, Detroit, performed the first split liver transplant in Michigan on two patients who were both dying from liver disease. At that time, fewer than 20 such procedures had been done nationwide.

Adult↗

New strategies for ER admissions.

Henry Ford Hospital, Detroit, operates a Level 1 emergency department. Last year, nearly 89,000 adults and children were treated; one-third were brought in with life-threatening conditions. This year, the emergency department expects to handle more than 100,000 patients. Patients with nonemergency problems sometimes wait four to six hours before being seen by a physician. Others get discouraged and leave.

Cooperative Behavior↗