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Biomedical subjects

D Angelucci

Publications and source records attributed to D Angelucci.

8 recordsLinked to original sources
PubMed1991

Rapid perinatal growth mimicking malignant transformation in a giant congenital melanocytic nevus.

Transformation to malignant melanoma in a giant congenital melanocytic nevus observed on the right limb of a 3,300-g newborn boy was strongly suggested by the histologic features of its ulcerated and papular areas: atypical melanocytes, irregular melanin distribution, many mitotic figures, "pagetoid" invasion of the dermis, and destruction of the rete ridges. Electron microscopy, too, showed that the atypical melanocytes had irregularly shaped and folded nuclei, one or more nucleoli, and a cytoplasm rich in organelles and polymorphous melanosomes. Investigation with a panel of monoclonal antibodies, on the other hand, revealed the antigen phenotype of a proliferative melanocytic lesion unaccompanied by the plain expression of antigens usually observed in malignant melanoma. In addition, the clinical picture during a 2-year follow-up has been free from signs of locoregional and systemic progression.

Antigens, Neoplasm↗
PubMedDate not supplied

Blueprint for proficient practice: an adult medical-surgical nursing orientation program.

Medical-surgical nursing is a specialty that is long overdue for acknowledgment. Our hospital orientation program provides an integration of theory and practical experience using the principles of adult learning. Faculty maintain "facilitator" rather than "instructional" roles and develop supportive and collaborative relationships with the new nurse. Its concise plan and design is intended to have a favorable impact on professional nursing practice and patient care outcomes. In addition, the program has promoted a recruitment advantage in today's arena of educational competitiveness.

Humans↗
PubMedDate not supplied

[Primary lymph node infarct and malignant non Hodgkin's lymphoma. Description of a case].

Primary lymph node infarction and malignant non Hodgkin lymphoma. Case report. We describe a case of spontaneous primary lymph node infarction in a patient who had diagnoseable malignant lymphoma on rebiopsy after a period of 35 days. The first node biopsy showed nearly complete homogeneous necrosis with loss of normal architecture and peripheral rim of organizing granulation tissue. A stain for reticulum, however, showed preservation of the nodal reticulum framework. The follow-up biopsy on the same cervical area, approximately one month later, surprisingly showed a large cell lymphoma. Comparison of reticulum stains of this neoplastic node with earlier stains should dispel any doubts that the first lymph node studied was a true case of non-neoplastic infarction. A review of the literature on lymph node infarction is reported.

Aged↗