PubMed Health⌕ Search

Biomedical subjects

D Angus

Publications and source records attributed to D Angus.

25 records · Page 2Linked to original sources
PubMedDate not supplied

Detection of mutagenic activity in human urine following fried pork or bacon meals.

Mutagenic activity has been demonstrated in urine of human subjects after ingestion of fried pork or bacon. Activity was detected with Salmonella strains TA1538 and TA98 particularly, in the presence of liver homogenate S9, and was not enhanced by prior incubation of urine with beta-glucuronidase. Chemical and biological characteristics of the urine activity closely resemble those found in extracts of fried pork and bacon which also increase the frequency of sex-linked recessive mutations in Drosophila melanogaster. Microwave-cooked meat neither contained extractable mutagenic activity, nor contributed to urinary mutagenicity, possible due to the paucity of browning reactions in meat cooked under these conditions. If the urine and meat factors are chemically identical, then approximately one-third of the food activity is recovered from the urine. These results show that mutagenic factors, generated during cooking of pork and bacon, are ingested and absorbed and are subject to urinary clearance in biologically detectable quantities. It is possible that the potential for genetic toxicity in humans of these and related factors has been underestimated.

Animals↗
PubMedDate not supplied

Guidelines for rescue training of the lay public.

The fundamental goal of emergency medical response in disaster is to save lives and reduce injury and permanent disability. It has been observed that urgent emergency medical care of seriously injured earthquake casualties trapped under building rubble, cannot be provided unless the victims have been extricated and transported to medical facilities by friends or relatives, or are accessible to field rescue and medical teams. Equally important is the fact that extrication of seriously injured, trapped victims by laypersons is hazardous, unless the following conditions are met: 1) the rescuer has basic knowledge of extrication, and; 2) there is early application of effective life-supporting first-aid (LSFA) and/or advanced trauma life support (ATLS) at the scene. Time is the critical factor in such an effort. In previous studies of death and dying in earthquakes, it was noted that extrication of trapped victims will be attempted by survivors. Therefore, it is suggested that citizens living in regions of high seismic risk and trained in basic search and rescue and in LSFA are the most immediate resource for early response after an earthquake. An accompanying paper addresses the issue of citizen LSFA training. This paper focuses on the basic concepts of search and rescue training for the lay public.

Disaster Planning↗
PubMedDate not supplied

Sustainable health care for Canada.

Sustainable Health Care For Canada is a synthesis of the research findings of the Cost-Effectiveness of the Canadian Health Care System Project initiated by the Economic Council of Canada. Upon the council's closing, the team moved to become part of the Queen's-University of Ottawa Economic Projects to complete the research. During the project, 18 working papers were produced, in addition to the research report and the synthesis report. In this article, the authors provide an overview of this large-scale research program and highlight some of its key findings.

Budgets↗