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Biomedical subjects

D Ardichvili

Publications and source records attributed to D Ardichvili.

At least 19 recordsLinked to original sources

[AL amyloidosis].

AL amyloidosis is a systemic disease caused by the deposition of fibrillar proteins in organs and tissues. These deposits are responsible for organic dysfunctions and may be rapidly lethal. Current therapy is unsatisfactory. We describe three clinical cases of multisystemic AL amyloidosis but with different initial presentation: nephrotic syndrome, cardiac failure and hepatic insufficiency. We review the literature about the clinical features, diagnostic methods and treatment of the disease.

Aged↗

Cyst of the gallbladder.

A cyst of the gallbladder is a very rare lesion. The possible causes of such an anomaly are reviewed. It may be acquired or congenital. The latter is particularly exceptional. A case of congenital cyst is reported and illustrated by various imaging techniques.

Cysts↗

Prenatal diagnosis of a pulmonary cyst by ultrasonography.

We report a patient in whom a prenatal diagnosis of an intrapulmonary cyst was made by ultrasonography. To our knowledge, no such case has been reported before and prenatal diagnosis permitted prompt management of an asymptomatic neonate.

Adult↗

[Megacalicosis].

Explore the source record for details and available documents.

Adult↗

Treatment with steroids of a giant cell granuloma of the maxilla.

This case report of giant cell granuloma involving the maxilla is of particular interest for two reasons: the locally aggressive clinical course contrasting with the diagnosis of a benign disease and the spectacular, although transient, response under steroid treatment. Corticotherapy should be further tested in cases of invasive or recurring giant cell granuloma.

Adult↗

A case of familial visceral myopathy with atrophy and fibrosis of the longitudinal muscle layer of the entire small bowel.

The case of a 21-yr-old man, who died in cachexia after 2 yr of intermittent abdominal pain, bouts of diarrhea, and anorexia, is reported. Laboratory tests performed shortly before death disclosed signs of malabsorption. Radiologic examination of the gastrointestinal tract showed a coarse mucosal relief in the upper jejunum and a tubular aspect in the rest of the small bowel. There was no dilatation of the loops. Autopsy revealed severe to complete atrophy with fibrosis of the outer muscle layer of the entire small bowel, extending from the pylorus to the ileocecal valve. The only other lesion discovered was a moderate portoportal fibrosis of the liver. The patient's brother had died a few months earlier after 2.5 yr of similar symptoms. An upper gastrointestinal series had shown dilatation of the stomach with fluid retention and a tubular aspect of the small bowel with generalized widening of the loops. No autopsy was performed. There was a high degree of consanguinity on the mother's side. Family history revealed no other evidence of possible genetic factors in the disease.

Adult↗