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Biomedical subjects

D Astolfi

Publications and source records attributed to D Astolfi.

24 records · Page 2Linked to original sources
PubMedDate not supplied

[Occlusive aorto-arteropathies: surgical treatment and long-term results in 4 cases treated surgically].

A rare disease with an obscure etiology is described. It affects predominantly the aorta and occasionally some of its branches, producing a decrease on the lumen vessel. In our experience it has been diagnosed in four young patients and the most important symptom has been arterial hypertension. In three cases the thoracic aorta was involved, with aneurysmal dilatation in one of them. In the rest the thoracic as well as the abdominal aorta were involved. All of them were treated surgically; on three, a latero lateral by pass was performed and in the fourth an aneurysmal resection was done and the aorta reconstructed with a dacron prosthesis. The clinical follow up 4 1/2 years later, showed normal arterial pressure, and patent by-passes, on angiography. We conclude that the revascularization technique can change the natural history of this disease.

Adolescent↗
PubMedDate not supplied

Post-infarction ventricular septal rupture: surgical considerations and results on five operated patients.

Five patients were operated on for ventricular septal rupture following myocardial infarction. The mean time interval between occurrence of infarction and surgery was 37 days (from 4 to 54 days). At EKG, the infarction site was anteroseptal in two cases and postero-inferior in three. Progressive deterioration of cardiac function leading to cardiogenic shock was noticed in four patients. Four patients had cardiac catheterization before surgery: the mean pulmonary to systemic flow ratio was 2.5:1 (from 3.8:1 to 1.8:1); in each case L.V.E.D.P., pulmonary wedge and pulmonary arterial pressures were elevated. Left ventricular angiograms and selective coronariograms were obtained in three patients, demonstrating the presence of left ventricular aneurysm in all three. In two patients, repair was performed through right ventriculotomy; in patients with left ventricular aneurysm, a left ventriculotomy and aneurysm resection were performed. This technique seems to permit much clearer view of the rupture site. In all patients the V.S.D. was closed by a dacron patch, reinforced with teflon pledgets. Two of the five patients died in the early postoperative period. Both had been operated within the first week from the onset of the ventricular septal rupture, because of cardiogenic shock, refractory to medical therapy. The three survivors showed remarkable improvement after surgery and they are in functional class II at a mean follow up period of 20 months. Emphasis is put on factors influencing surgical treatments and prognosis of these patients.

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