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D Aygun

Publications and source records attributed to D Aygun.

7 recordsLinked to original sources
PubMed2004

Fibrous dysplasia of the frontal sinus: an uncommon cause of frontal lobe abscess.

Fibrous dysplasia of the cranial air sinuses is rarely reported in the literature. This is the first report of frontal lobe abscess (FLA) associated with fibrous dysplasia of the frontal sinus (FDFS). A 29-year-old female presented with seizures and acute confusion. Cranial computed tomography (CT) revealed fibrous dysplasia of the left frontal sinus and associated FLA. She was referred to the neurosurgical service and the abscess and dysplastic tissue were removed. Histological examination confirmed fibrous dysplasia. We review the radiological appearance of FDFS with FLA. Clinicians should be aware of the association between these two conditions.

Adult↗
PubMed2004

Neurological soft signs in obsessive-compulsive disorder.

BACKGROUND: Neurological soft signs (NSSs) are defined as abnormal motor or sensory findings, including involuntary movements, a variety of dispraxia, difficulties in performing rapid alternating movements, difficulties in two-point discrimination, and graphesthesia in a person without a neurological disorder which can be determined as its focus. AIMS: to investigate the relationship of NSSs with obsessive-compulsive disorder (OCD). SETTINGS AND DESIGN: This study was designed in the Psychiatry Polyclinic of Ondokuz Mayis University Hospital. After signing an informed consent form, all the subjects were divided into 2 groups: (1) the patient group and (2) the control group. MATERIAL AND METHODS: Thirty consecutive patients presenting with DSM-IV OCD were included in this study. The control group consisted of 30 healthy subjects without a psychiatric/neurological disorder. All subjects underwent a physical and neurological examination for soft signs (PANESS). STATISTICAL ANALYSIS USED: The Mann-Whitney U test was used for statistical analysis of data. RESULTS: It was seen that graphesthesia, two-point discrimination, and total PANESS scores were significantly higher in the group with OCD than the control group. In other NSSs, there was no significant difference between the patient and control groups. CONCLUSIONS: Unlike some studies, in the present study, the difference between the groups in graphesthesia compared to other NSSs was significant. The results of this preliminary study suggest that there is a relationship between NSSs and OCD. We think that NSSs may point to a structural brain abnormality in patients with OCD.

Adult↗
PubMed2003

Clinical warning criteria in evaluation by computed tomography the secondary neurological headaches in adults.

Our aims were to investigate the frequency of intracranial lesions detected by cranial computed tomography (CT-scan) amongst adult patients who had clinical warning criteria (CWC) for secondary neurological headaches and to determine the importance of CWC in predicting a possible lesion on CT-scan. Seventy consecutive patients with headache exhibiting CWC were included in this prospective study. The CWC included: (i) increase in the intensity and frequency of headache; (ii) abrupt onset of headache; (iii) persistence of headache despite analgesics; (iv) alteration of the characteristics of headache; and (v) presence of focal neurological symptoms or findings. The mean age of the patients was 46.5 years; the female-to-male ratio was 1.5. Of the patients, 35.7% had a neurological cause identified by CT-scan, and 64.3% had normal CT-scan. In the patients without lesion, of headaches, 64.4% were primary, and 35.6% were from undefined headache group. Although, of the above criteria, only the 5th was different markedly in the patients with lesion than the patients without lesion, in evaluation by CT-scan the secondary neurological headaches in adults, all CWC should look for absolutely in their history and physical examination.

Adult↗
PubMed2003

Electrocardiographic changes during migraine attacks.

OBJECTIVES: To clarify whether electrocardiographic (ECG) changes can be identified during a migraine attack and to determine whether there are ECG differences between periods with and without headache. BACKGROUND: The clinical signs and symptoms of migraine point to involvement of the autonomic nervous system, and especially to disrupted regulation of the circulatory system and autonomic balance. This disruption may be more marked during a migraine attack. During a migraine attack, autonomic imbalance within the heart and its vessels conceivably may result in ECG abnormalities. METHODS: In 30 patients with migraine, the ECG variables of heart rate, abnormalities of rhythm, PR interval, QRS duration, corrected QT interval, T inversion, and ST-segment changes were recorded during migraine attacks and pain-free periods. RESULTS: Of the 30 patients studied during a migraine attack, 9 (30%) had one or more abnormalities of rhythm (including sinus arrhythmia, atrial premature contraction, and ventricular premature contraction), 20% had PR intervals greater than 0.20 seconds, 40% had corrected QT intervals greater than 0.44 seconds, 66% had T inversion, and 40% had ST-segment abnormalities. No patient had arrhythmia, PR intervals greater than 0.20 seconds, or corrected QT intervals greater than 0.44 seconds during a pain-free period. No differences were noted for ST-segment changes, T inversion, and total ECG changes between periods with and without headache, but both PR and corrected QT intervals were significantly longer during migraine attacks than during pain-free periods. CONCLUSIONS: We conclude that ECG abnormalities often are present during a migraine attack, and for most of these, particularly PR and corrected QT interval lengthening, these abnormalities will be absent or less prominent during pain-free intervals.

Adult↗
PubMed2002

Basic toxicological approach has been effective in two poisoned patients with amitraz ingestion: case reports.

Amitraz, a formamidine insecticide and acaricide used in veterinary practice, presents side effects in humans related to its pharmacological activity on alpha 2-adrenergic receptors. There is little information available in the literature about the toxicology of the product in man and the treatment of this poisoning. In this report, the clinical and laboratory features of amitraz poisoning in two patients by a veterinary formulation also containing xylene are presented. The major clinical findings were unconsciousness, drowsiness, respiratory failure requiring mechanical ventilation, miosis, hypothermia and bradycardia. The laboratory findings were hyperglycemia, hypertransaminasemia and increased urinary output. Supportive management of this poisoning in humans is suggested in only a few articles and there is no specific antidote for the subsequent possible pharmacological effects of amitraz. In our two cases, we performed supportive treatment such as mechanical ventilation, atropine, gastric lavage, active carbon, oxygen and fluid administration. We concluded that the basic approach to the patient with amitraz poisoning, including initial stabilization to correct immediate life-threatening problems, treatment to reduce absorption and measures to improve elimination of the toxin, is effective.

Adult↗
PubMedDate not supplied

The clinical and electrophysiological features of a delayed polyneuropathy developing subsequently after acute organophosphate poisoning and it's correlation with the serum acetylcholinesterase.

INTRODUCTION: Organophosphorus-induced delayed polyneuropathy (OPIDP) characterised with cramping pain, paresthesias in the lower extremities and occasionally in the hands, followed by weakness of the distal limb muscles, especially in the legs, and partial denervation of affected muscles often develops within first 3 weeks following acute poisoning. OBJECTIVES: To determine the incidence of development of subsequent polyneuropathy among patients with acute organophosphate poisoning (OPP), to assess whether there was a difference between patient groups with severe poisoning and mild poisoning for the development of polyneuropathy, to determine whether there was a correlation between the serum AChE levels and the development of OPIDP, and to define the clinical and electrophysiological features of OPIDP. METHODS: Forty-one patients with acute OPP admitted to the Emergency department were included in this retrospective study. On days 1, 2, 3, and 7, each patient was assessed clinically, with the measurement of serum AChE, and results were recorded on special forms. RESULTS: OPIDP was diagnosed clinically in 14 patients (34.15%) during the 14th to 22nd days after poisoning. Twelve (85.7%) of 14 patients had a severe clinical status on day 1 after poisoning. The frequency of development of OPIDP was higher in the patients with severe poisoning than the patients with mild poisoning (p = 0.041). There was no significant correlation between the serum AChE levels and the development of OPIDP. CONCLUSION: We conclude that the serum AChE levels measured on the first day and consecutive several days can not be the predictive of the development of subsequent OPIDP.

Acetylcholinesterase↗