PubMed Health⌕ Search

Biomedical subjects

D Azoicăi

Publications and source records attributed to D Azoicăi.

At least 19 recordsLinked to original sources

[The epidemiological aspects and prevalence of markers in those with viral hepatitis C in some population categories in 1994-1997 in Iaşi County].

The results of the epidemiological, clinical and laboratory investigations, carried out in the 1994-1997 interval in the Iaşi district, on various populational groups, to indicate the prevalence of the antibodies anti-HVC possessors are presented. In 3611 patients with clinical-epidemiological HCV diagnosis, it was recorded a prevalence of the anti-HCV antibodies (AcHCV) presence of 22.7%. Posttransfusional hepatitis, epidemiologically diagnosed in 205 hospitalised patients was attributed to HCV in 11.6% of the cases, and in 94 patients with neurological diseases, AcHCV were identified in 9.6%. The presence of AcHCV at 825 persons in medico-sanitary staff, from risk domains, has recorded a prevalence of 8.0%. In the January 1997-September 1997 interval, the investigation by IIIrd generation ELISA of 51,149 blood samples of donors from various areas indicated the presence of AcHCV with an interval average of 2.6%.

Blood Donors↗

[Epidemiological considerations of the arbo- and arenaviruses].

The complex epidemiological process of arboviral and arenaviral diseases, their dependence on a multitudine of etiologic agents, the risk of severe manifestations, absence of a specific treatment and difficulties in preparing the vaccines, place these diseases among those of high concern at national and international level. The multidisciplinary investigations carried out in Moldavia by M. Duca, Eugenia Duca, Gr. Teodorovici, Alla Vâţă, St. Dumitriu, V. Luca, D. Buiuc, A. Ivan and others have elucidated numerous aspects regarding the epidemiology and prevention of arboviral diseases. The increased morbidity by meningitis and meningoencephalitis recorded in Romania the interval summer--early fall 1996 was attributed based on serologic diagnosis, to West Nile virus. The etiological investigations were done both in our country (Cantacuzino Institute, Institute of Virology, Laboratory of the Ministry of National Defence) and abroad (Pasteur Institute at Paris, Colindale Institute London, CDC, Atlanta, USA). For the Romanian population the risk for a periodical re-emergence of some arbovirus diseases is due to favorable local conditions with the relationships with geographical areas were these diseases have and endemic-epidemic evolution are added.

Arbovirus Infections↗

[The importance of the use of selenium in the role of an antioxidant in preventing cardiovascular diseases].

The evaluation of the results of the oxygen free radicals (RLO2) formation is a current subject in biology and medicine. The oxidative stress, which is the altering of the balance between the higher activity of oxygen and the enzymatic or nonenzymatic protection systems, may be one of the causes that starts and aggravates a disease. In this context, the supplementation of the diet with selenium, superoxide dismutase, vitamins A, C, E, is considered a primary prevention measure (for the apparently healthy persons) and a secondary one (for those with advancing forms of disease) that is both efficient and modern by utilization of some "drug-food" products. The transversal study realized on a group of 39 blood donors presence of the cardiovascular risk determined by the raising of the prevalence of some atherogenic factors (active smoking, hypercholesterolemia) which is also expressed by the lowering of the level of some oxidative stress indicators (glutathione peroxidase--GSH-Px < 0.139 moli/ml and catalase < 2.20 U/ml). The simultaneous low intake of selenium from the central drinking water supplies in the city of Iaşi (0.1-1 g/l) has permitted us to consider necessary the diet supplementation both with foods rich in vitamins with an antioxidant role and with specific medication with selenium, as a protective micro-element.

Adult↗

[The concordance and discordance of cardiovascular risk factors in a group of twin children].

The cross-sectional study of epidemiological screening type has permitted to evaluate some cardiovascular risk factors in two groups of monozygotic (MZ) and dizygotic (DZ) twins born between 1975-1990, in the town of Iaşi. In the 89 MZ pairs and 112 DZ pairs, certain constitutional and behavioural cardiovascular risk factors have presented values of prevalence with statistical signification (p < 0.05) in terms of their age, sex, the urbanisation time and the educational level of their parents. In risk factors existence or absence to both of the twins have put into evidence, to the MZ, most enhanced values of concordance as regards: overweight (66.6%), excessive consumption of salt (56.9%), food with atherogenic risk (50.9%). The concordance values have been less in DZ compared to MZ concerning all the risk factors excepting compartmental type A (77.7%). By analysing the concordance variants, an preponderant influence of the environment has been noted in the studied MZ and heredity and environment influence in DZ. By measuring the arterial blood pressure values at the twins and the twins parents, a prevalence of the essential arterial hypertension is noticed to both of the twins, 6.2% in MZ pairs and 6.9% in DZ ones.

Adolescent↗

[Epidemiological observations on the physical activities of patients with arterial hypertension].

The authors point out the results of some multidisciplinary epidemiological researches concerning the relation between the multifactorial etiology of arterial hypertension (AHT) in employers working in two factories and the nature of physical activity. The results show that the highest percentage of AHT cases is in the persons which do not have physical activity (occupational, housing or leisure). The women with AHT, which are frequently supra-ponderously, make a low level of physical activity. They have effort respiratory modifications in 40% of cases. The decreasing interest for control and prevention of health risks of the level of occupational health services has medical and social negative effects on long term.

Adult↗

[National statistical parameters of cervical cancer in Romania: 1992-1997].

UNLABELLED: Cervical cancer is an important health issue in Romania, as the 1990-1992 statistics of IARC mentioned it to be first in Europe as mortality through this neoplasia. We bring to 1997 the national statistical data regarding the cervical cancer. MATERIAL AND METHODS: Our data provided by the Romanian Health Ministry statistical Office allowed estimations over the following parameters: incidence (crude and age-related), prevalence and number of deaths, and relationships between these parameters and age group, clinical stage, geographical distribution, etc. Usual statistical methods of interpretation are used, as well as prognosis using the parabola methods, and world-standardized incidence rates. RESULTS: Between 1992-1997, there were 14743 new cases of cervical cancer diagnosed in Romania. The crude incidence per 100,000 was 21.27, and age-related incidence ranged between 0.27 per 100,000 for the under 20 to 46.73 in the 40-49 group. World standardized incidence rate indexed by age groups gave an incidence of 16.84. The mortality was 2.37, with world standardized age related deaths of 2.81. The clinical stage distribution showed stages 0 (15.02%), I (14.04%), II (34.91%), III (27.81%) and IV (8.19. The incidence and mortality data shows a better evolution for younger age groups, but a steady increase in 30-39 group for incidence and mortality. CONCLUSIONS: The data above place Romania on a stable but high incidence of cervical cancer, with a high mortality due to late diagnostic and socio-economical conditions.

Adult↗

[Occupational stress--risk factor in essential arterial hypertension].

The stress was recorded taking into consideration the epidemiological interview, using a standard methodology by filling in the type card the occupational stress (OS) and the family stress (FS). The constitutional factors (behaviour type A, body weight index > 25 Kg/m2) as well as the consumption in excess of salt, have significantly correlated themselves, both in individuals with OS and FS, and in those with the exclusively OS. The modification of biochemical constants (total cholesterol, triglycerides, total lipids, HDL-cholesterol, LDL-cholesterol) significantly associate themselves in persons to which the presence of OS and FS, of the occupational one, respectively was put into evidence (chi 2 = 94.10 for 5 freedom degrees and p < 0.001, chi 2 = 118.94 and p < 0.001, respectively). The prevalence of persons with pathologic values of total lipids was 58.7%, of triglycerides 35.7%, of total cholesterol 12.7%, of LDL cholesterol 27%, and of HDL-cholesterol 44.4%. Measuring the values of systolic and diastolic arterial hypertension an increase above the normal values of limit systolic arterial hypertension at 23.8% and at 12.3% for illness systolic arterial hypertension was found. The evaluation of association of certain cardiovascular risking factors in individuals with occupational stress has permitted a global understanding, useful for the elaboration of some preventive programmes.

Alcohol Drinking↗

The prevalence of the owner of serologic markers for the hepatitis C virus, in a north-eastern territory of Romania.

The paper describes aspects in the natural evolution of hepatitis C virus (HCV) infection with severe outcomes induced by the typical or atypical clinical manifestations or chronic carrier state. In the interval 1995-1999 in the Iasi district morbidity from all types of viral hepatitis ranged from 153.4 cases per 100,000 inhabitants in 1995 to 66.6 in 1999. The features of A viral hepatitis epidemiological process was the multiannual cyclic pattern. From estimating the circulation of HCV in the population of Iasi district, several population categories have been screened for the presence of HCV antibodies (anti-HCV). Testing 87,894 blood samples assessed the prevalence of anti-HCV in blood donors. Different annual values resulted: 1.5% in 1997 and as a result of routine screening, only 0.3% in 1999. The cases of posttransfusion hepatitis (PTH) admitted to the Clinic of Infectious Diseases of Iasi, the diagnosis of which was supported by epidemiological history and confirmed serologically by the presence of anti-HCV were of 12 in 1995 (36.4% of all PTH), 20 in the interval 1996-1999, with an average for the 4 study years of 7.5%. Anti-HCV was found in 24.4% of series of 4,594 patients with viral hepatitis, in 32.1% of 582 individuals with various disorders or at risk, of which those with liver cirrhosis accounted for 37%, and in 9.6% of 94 patients with neurological disorders. Of the 1083 tested physicians and nurses working in health care settings at risk 6.6% were anti-HCV-positive.

Biomarkers↗

[Two decades of epidemiologic surveillance of the evolution of viral hepatitis in Iaşi County (1971-1990)].

The results of epidemiological observations on the evolution of viral hepatitis in the Iaşi district in the interval 1971-1990 are presented. A mean morbidity of 251.2 cases/100,000 inhabitants, this being in most years under the national mean, was found. In 75.9% of all cases the infections caused by hepatitis viruses affected the age-groups 1-14 years, indicating a high incidence of hepatitis A... Hepatitis B had a more increased incidence in the children aged 0-1 year, then it decreased but was present in all age groups. Although recorded all year round, increases in the incidence of viral hepatitis A were noticed during fall and winter seasons, prevailing in the children and teenagers collectivities.

Adolescent↗

[Epidemiological observations on the significance of the relations between elevated values of essential arterial pressure in schoolchildren and their parents].

The results of an epidemiological screening of 1,228 parents and 614 children, pupils in the V-XII forms of 12 schools of different types, are presented. It is suggested that when parents present elevated blood pressure values their children, although normotensive, are at high risk, especially in case more risk factors are present. The relation hypertensive parents--hypertensive offsprings was strongly significant. In the hypertensive children with normotensive parents the high frequency of some life-style dependent risk factors is discussed. The relationship between risk factors and morbidity by essential hypertension both in parents and their offsprings and the need of primary and secondary prevention programs for pupils are underlined.

Adult↗

[Epidemiological and laboratory observations on viral hepatitis morbidity in child social welfare institutions].

The investigations revealed that in the interval 1978-1987 the mean incidence of viral hepatitis type B in children was 40 at 100,000 inhabitants as compared to 767 in the children from orphanages. In 27.5% of the cases, the children from orphanages, with or without HBs antigen, had viral hepatitis in their case history. The prevalence of AgHBs carriers was of 21.6%, the highest value (46.1%) being recorded in the children from orphanages in the age group 0-3 years. It was also found that 14.9% of the children had AgHBs when admitted to orphanage and 28.7% became carriers later on. It is suggested that in children homes there are conditions for an increased risk requiring special measures for viral hepatitis prophylaxis and control.

Age Factors↗