Biomedical subjects

D B Lillie

Publications and source records attributed to D B Lillie.

5 recordsLinked to original sources

PubMed1984

Experience with hypercalcemia and osteoporosis of neoplastic disease.

Hypercalcemia and hypercalcemic crisis are common and often life threatening complications of neoplastic disease. Even moderately increased mobilization of skeletal calcium can result in significant osteoporosis. This in turn can give rise to pathologic fractures, often followed by pulmonary fat embolism and death. Bone pain is at times the first sign of neoplastic disease and the reason for seeking medical help.

Adrenal Cortex Hormones↗

PubMed1984

Effect of sodium meclofenamate on radiation-induced esophagitis and cystitis.

Stumptailed monkeys (Macaca arctoides) received 2000 rad irradiation to the upper half of the esophagus and to the bladder by a 6-MEV linear accelerator. Endoscopy and biopsy was obtained from these organs weekly for 3 weeks. At the end of this period, the animals were autopsied and histopathologic examination undertaken. Sodium meclofenamate in doses of 5-20 mg/kg/day p.os was found effective in reducing or preventing radiation induced esophagitis and cystitis.

Animals↗

PubMed1983

The role of the tissue adhesive fibrin seal (FS) in esophageal anastomoses.

Following surgical removal of esophageal tumors, leakage and mediastinitis is a frequent and often fatal complication. A new method has been developed to seal suture lines in the esophagus with preparations containing fibrinogen, cold insoluble globulin, factor XIII, antiplasmin, platelet growth factor, thrombin, and calcium chloride. In experimental animals operated on by standard methods, esophageal leakage developed in 50% of the animals and death in 40%. By contrast, in treated animals, esophageal leak and death developed in only 20%. More adhesions were found in treated animals than in control animals.

Animals↗

PubMed1981

Experimental evidence of increased ipsilateral gentamicin nephrotoxicity after unilateral ureteral obstruction.

This study describes an experimental model for the investigation of nephrotoxicity in which the aminoglycoside, gentamicin, is given after unilateral ureteral obstruction is produced. The preliminary findings indicate a significantly more severe loss of renal function in the obstructed kidney which receives gentamicin than in the obstructed kidney which does not.

Acute Kidney Injury↗

PubMedDate not supplied

Impotence.

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Erectile Dysfunction↗