Congenital skin defects, twins and toxoplasmosis.
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Biomedical subjects
Publications and source records attributed to D B McCrossin.
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58 paediatric patients with pneumonia, in whom an etiological agent had been isolated, were reviewed. The patients were designated to have either viral or bacterial pneumonia on the basis of proposed clinical and radiological criteria. These presumed diagnoses were then compared to the microbiologically proven diagnosis. When clinical features suggested a bacterial infection the chance of isolating a bacteria as opposed to a virus was 18%. Was radiological features suggested a bacterial infection the chance of isolating a bacteria as opposed to a virus was 30%. Thus the commonest cause of "bacterial" clinical and radiological features is a viral infection and the proposed criteria do not allow differentiation of bacterial from viral pneumonia.
Five paediatric cases of herpes simplex virus encephalitis are described. In each case the diagnosis was made with some difficulty. A high index of suspicion is required in order that appropriate diagnostic and therapeutic manoeuvres are initiated at an early stage of the illness.