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Biomedical subjects

D B Mendelsohn

Publications and source records attributed to D B Mendelsohn.

At least 19 recordsLinked to original sources

Corpus callosum lesions after closed head injury in children: MRI, clinical features and outcome.

Thirty-four children who sustained moderate to severe closed head injury underwent magnetic resonance imaging (MRI). Eight (24%) had MRI evidence of corpus callosum injury, most commonly within the posterior body and splenium. In contradistinction to reports in adults, there was no definite relationship between callosal injury and lower initial Glasgow Coma Scale scores, nor was there a significantly higher incidence of primary brain-stem lesions, diffuse axonal shear injury or intraventricular hemorrhage. In none of these 8 children did the initial admission computed tomography show evidence of callosal injury. Callosal injuries on MRI are not necessarily a poor prognostic finding, the majority of the 8 children showing good functional recovery.

Adolescent

The neuroradiology of visual disturbances.

The neuroradiology of visual deficits has advanced dramatically in recent years. Plain film evaluation of the orbit and face remains useful in the emergency room for the evaluation of trauma. High-resolution coronal CT remains the method of choice in the assessment of serious injury to the orbit and in cases of penetrating metallic foreign body. The contrast-enhanced orbital CT provides useful information in cases of tumor and infection and when the bones of the face or skull are involved. MRI has largely replaced CT in the search for brain infarct, brain tumor, and cerebral inflammatory and demyelinating processes. MRI is the study of choice in all cases of sellar and parasellar disease. It offers high-resolution images in any plane. GTPA enhancement has provided additional information from MRI without significant risk. The final selection of an imaging modality should be based upon the clinical presentation and any physical limitations of the patient.

Brain Neoplasms

Chondrosarcoma of the head and neck--the value of computed tomography.

Chondrosarcomas of the head and neck represent a small percentage and differ in their treatment and prognosis compared with chondrosarcomas elsewhere. Four different cases of chondrosarcoma are presented. One arose intracranially, two in the jaws, one of which followed irradiation for a retinoblastoma, and the last represents chondrosarcomatous transformation in cervical spine Paget disease which is exceptionally rare. Computer tomography (CT) plays an important role in delineating the extent of the tumor with visualization of bony destruction, associated soft-tissue mass, and calcification, information which is extremely important for surgical and therapeutic planning. CT can be vital in suggesting the best possible site for biopsy which is particularly important in this group of neoplasms where the histological diagnosis may be difficult.

Adult

Computed tomography in the diagnosis and treatment of mandibular ameloblastoma: report of cases.

Treatment of ameloblastoma is based on clinical manifestations and radiological features. The value of routine radiographs in determining the extent of the lesion may be limited. Four cases of mandibular ameloblastoma were studied using axial and coronal computed tomography (CT). The soft-tissue mass, destruction of cortical bone, and extension of tumor into the infratemporal fossa and adjacent structures were clearly visualized. These features demonstrate the superiority of CT over conventional radiography in delineating the extent of the lesion, which may be essential to its management.

Adult

Nasopalatine duct cyst.

The nasopalatine duct cyst appears to be an aggressive and symptomatic condition in the South African black population group. Of a total of 114 cases, 30 patients, all blacks, had cysts in excess of 30 mm in diameter. Two patients with large nasopalatine duct cysts, one of which was infected, underwent computed tomography. Computed tomography is an excellent method of demonstrating the extent, bony destruction and relationship of the lesion to neighbouring structures. A review of the subject with clinical and radiological features is presented.

Adult

Intracerebral pneumatoceles following facial trauma: CT findings.

Three patients with delayed frontal intracerebral pneumatoceles following facial injury are presented. In one patient an unusual appearance of bilateral and symmetrical frontal lobe pneumatoceles was demonstrated. While diagnosis is not difficult on routine radiographs, CT is valuable for determining effects on the brain and clearly delineating the fracture site; CT shows the location of the pneumatocele and may show an associated air-fluid level, mass effect or surrounding edema, or rim enhancement following administration of contrast material. The radiological appearances in conjunction with the clinical findings are highly characteristic and should not be mistaken for gas-forming cerebral abscesses.

Adolescent

Migratory redundant lumbar nerve roots. A case report.

A case of migratory redundant cauda equina nerve roots is presented. The redundant roots, seen initially below a spinal stenosis, were shown on repeat study after a short interval to have migrated above the level of stenosis, leaving the lower nerve roots with a normal appearance.

Cauda Equina

Atypical findings on computed tomography in tuberous sclerosis. Case reports.

In 3 patients with tuberous sclerosis computed tomography showed numerous low-density areas suggestive of brain demyelination. In addition, solitary small subependymal calcifications were noted. These features in an infant or child with unexplained seizures should alert one to the diagnosis of tuberous sclerosis.

Cerebral Cortex

Hysterosalpingography in the assessment of infertility in black patients.

A series of 200 consecutive hysterosalpingograms for the evaluation of infertility in Black women attending a clinic at the Hillbrow Hospital, Johannesburg, is reviewed. A fallopian tube abnormality was found in 81,8% of cases, terminal hydrosalpinx being present in 64,4%. A uterine abnormality was present in 25% of cases. In comparison with other series it appears that our incidence of tubal lesions, especially terminal hydrosalpinx, is the highest yet reported. A high correlation with laparoscopic findings (75%) is documented. In our infertility clinic hysterosalpingography is one of the most valuable tools in the initial evaluation of the infertile couple.

Adult

Computed tomographic appearance of laryngoceles.

The diagnosis of laryngoceles is usually not difficult and can be made clinically and by conventional radiological methods. Computed tomography is a useful, non-invasive, complementary method for confirming the diagnosis especially in complicated cases.

Dilatation, Pathologic

In utero diagnosis of a vein of Galen aneurysm by ultrasound.

A large midline supratentorial cystic lesion with associated cardiomegaly was seen in utero by ultrasound during the 34th week of pregnancy. The provisional diagnosis of a vein of Galen aneurysm was confirmed with CT and angiography after birth.

Adult

Computed tomography of the infratemporal fossa in primary jaw pathology.

Due to the anatomical relationship of the jaws to the infratemporal fossa this area is readily involved in pathological processes of the jaw. Conventional radiographs play a limited role in demonstrating this region. A variety of primary diseases of the jaws, namely hereditary, developmental, infective, benign and malignant tumours with extension into the infratemporal fossa, are presented. Computed tomography is an excellent method for showing both osseous and soft-tissue components which include bony destruction, new bone formation, soft tissue calcification, inflammatory and malignant processes affecting the muscles and fat in the infratemporal fossa.

Adolescent

Delayed splenic rupture: a true entity.

Two cases of secondary haemorrhage into subcapsular haematomas with delayed splenic rupture are presented. Ultrasound and computed tomography were essential in the diagnosis. In one of the cases a large splenic laceration was diagnosed by these two techniques 23 days following trauma. Ultrasound is of particular value and can be performed with ease in the clinical follow-up of patients who have sustained multiple injuries requiring immobilisation and orthopaedic traction.

Adult

Chondrosarcoma of the maxilla.

A case of chondrosarcoma of the maxilla with axial and coronal computed tomography is presented. The value of this new modality over conventional radiographs is discussed. A cartilagenous malignancy was suggested by a soft tissue mass with calcification. In addition there was lysis and osteoblastic bony reaction. Tumour extension into neighbouring structures is excellently demonstrated.

Biopsy