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D B Moore

Publications and source records attributed to D B Moore.

27 records · Page 2Linked to original sources

Suppression-burst pattern associated with generalized epileptiform discharges and alpha-theta pattern coma.

In this paper we reported a patient with multisystem failure, whose EEG immediately preceding death demonstrated a unique combination of suppression-burst pattern, generalized epileptiform discharges, and alpha-theta pattern coma. Post-mortem examination showed ischemic-anoxic lesions involving cortical and sub-cortical gray matter. The lack of white matter pathology in our patient indicates that white matter lesions may not be involved in the pathogenesis of the above EEG patterns in anoxic encephalopathy.

Aged↗

Localization of the parathyroid glands by intraoperative methylene blue staining.

Exploration of the neck for primary hyperparathyroidism has increased in our institution, as evidenced by nine patients treated in the past one year, as compared with six in the previous three years. Our experience indicates that methylene blue staining has served as an important adjunct in the localization of abnormal parathyroid glands. No complications were noted intraoperatively or postoperatively as a result of its use. Operating time was measurably decreased. The results of this study support the routine use of methylene blue in both primary and secondary parathyroid exploration, and this is currently being done in our institution.

Adenoma↗

Periappendicitis: Clinical reality or pathologic curiosity?

The data from a retrospective study of 224 patients with preoperative diagnosis of acute appendicitis are presented. Periappendicitis was subsequently diagnosed in 5.4 per cent of these patients. More than half of these patients with periappendicitis had other intraabdominal disease demonstrable at operation. The remaining patientw with periappendicitis were followed for two years, and long-term complications were not observed. It is concluded that periappendicitis does not represent an unrecognized nonappendiceal process that requires special management.

Acute Disease↗

Alteration in temperature regulation induced by burn injury in the rat.

The preoptic anterior hypothalamus (POAH) of rats housed at three ambient temperatures was implanted with perfusion apparatuses. Response of heat production to displacement of POAH temperature was determined for control animals and animals with burns (31% +/- 3% total body surface area). At an ambient temperature of 22 degrees C there was a significant increase in thermosensitivity of the POAH for both control rats and rats with burns compared with thermosensitivity at 32 degrees C. Within ambient temperatures there was no effect on thermosensitivity detected for rats with burns compared with control rats. The threshold temperature for heat production was shifted significantly upward (p less than 0.05) both by a lower ambient temperature and by burn injury. The reference temperature for heat production was also shifted to the right by burn injury (p less than 0.05). The significant shifts to the right for threshold temperature and reference temperature for heat production enhance the organisms's ability to meet the stress of the hypermetabolic response. At a warm ambient temperature (32 degrees C) there are no significant differences in thermoregulation detected in animals with burns or control animals.

Animals↗