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D B Shear

Publications and source records attributed to D B Shear.

5 recordsLinked to original sources

Sinus tarsi syndrome: the importance of biomechanically-based evaluation and treatment.

The diagnosis and treatment of lateral foot pain is often difficult. The differential diagnoses are numerous, including osseous abnormalities, sprains, peripheral mononeuropathies, and radiculopathy. An often overlooked cause of lateral foot pain is sinus tarsi syndrome. From a review of the literature, it appears that even when the diagnosis of sinus tarsi syndrome is made, the biomechanics of the foot and ankle are not considered. The following is a case study of a patient with sinus tarsi syndrome treated successfully through biomechanical evaluation, and fabrication and use of custom-molded orthoses.

Aged

A chemical relaxation study of human prostatic acid phosphatase.

Chemical relaxation methods and a dilution technique were applied to the study of the hydrolysis of p-nitrophenyl phosphate by human prostatic acid phosphatase. Although the reaction mechanism was not elucidated, rate constants and equilibrium constants were obtained for the reaction of enzyme and p-nitrophenol to form a complex. A slow, 2-sec relaxation effect which showed no concentration dependence was observed in various reaction mixtures, including some lacking the substrate and products of the hydrolytic reaction. The conclusion drawn is that there are two forms of the prostatic enzyme, which are normally in equilibrium with each other, but which undergo a relatively slow interconversion when this equilibrium is perturbed. A preliminary calculation indicates that these forms are present in the equilibrium ratio of 2:1.

Acid Phosphatase