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Biomedical subjects

D B Soll

Publications and source records attributed to D B Soll.

18 recordsLinked to original sources
PubMed1990

Management of the paralyzed lower eyelid by implanting auricular cartilage.

The success of a procedure to reanimate paralyzed eyelids is determined by the functional and cosmetic results. When the cornea is covered during blinking and sleeping, function has been restored, while a pleasing cosmetic result has been achieved if the eyes appear symmetrical when the lids are open. Several procedures have been developed to restore closure of the paralyzed upper eyelid (implantation of gold weights or open wire springs) or to correct lower lid lagophthalmos and ectropion (lower lid tightening with a Bick procedure or insertion of a closed eyelid spring). In some cases, even a combination of the Bick procedure and insertion of a spring may be insufficient to correct lower lid droop; therefore, we developed a technique to place cartilage into the lower eyelid to correct lid droop. The procedure, suggested by one of us (D.B.S.), has been performed on 51 patients to date. This article reviews our experience with these 51 consecutive patients.

Ear Cartilage↗
PubMed1989

Kaposi's sarcoma of the eyelid as the initial manifestation of AIDS.

Early recognition and identification of acquired immune deficiency syndrome (AIDS) ocular manifestations are mandatory if proper precautions are to be taken. Kaposi's sarcoma is a well-known manifestation of the disease; however, the initial presentation of the lesion on the eyelid is rare. Such a case is presented in order to alert ophthalmologists to this. It is suggested that all eyelid lesions in suspect patients should be regarded as potentially related to AIDS.

Acquired Immunodeficiency Syndrome↗
PubMed1988

New surgical approaches to the management of ocular exposure secondary to facial paralysis.

Restoring dynamic eyelid function in patients who experience facial paralysis is a difficult problem. Some procedures necessary to protect the globe, such as tarsorrhaphies, may be cosmetically disfiguring and functionally disabling. Several surgical procedures may be used in combination to restore function and, at the same time, achieve satisfactory cosmesis. The use of gold weights and ear cartilage grafts is described. In the author's experience, the use of this combination produces very good results.

Cartilage↗
PubMed1987

Methotrexate-anticollagen conjugate inhibits in vitro lens cell outgrowth.

After-cataract, or posterior lens capsule opacification, is an undesirable but common sequela to extracapsular cataract surgery. We are investigating biochemical means to prevent after-cataract formation, which can be applied at the time of the original surgery. Based on similar research efforts in cancer chemotherapy, we have prepared a conjugate of the antimetabolic agent methotrexate with an antibody specific for basement membrane collagen, the major protein in the lens capsule. The conjugate was evaluated using biochemical measurements, and retained both antimetabolic and antibody activities. When the conjugate was applied to bovine posterior capsules in vitro, or in vivo in rabbits, it was an effective inhibitor of lens epithelial cell outgrowth in cell culture.

Animals↗
PubMed1986

Drugs and glaucoma.

Explore the source record for details and available documents.

Adrenergic beta-Antagonists↗
PubMed1979

Basic concepts and an overview of cryosurgery in ophthalmic plastic surgery.

In cryosurgery, a rapid double freeze using liquid nitrogen spray coupled with a slow thaw generates optimum cell destruction. Important factors in using the cryosurgical technique include temperature monitoring of the lesion, the type of instrumentation, the type of cryogen, and the nonhomogeneity of human tissue. Physiological processes occurring subsequent to cryogen application cause tissue necrosis. Cryosurgery is indicated for treatment of some basal cell carcinomas and occasional squamous cell carcinomas; most other lesions should be treated by surgical excision at the present time. The authors are involved in research to determine means of observing tissue destruction, temperature monitoring and control methods, and evaluation of post-thawing processes.

Animals↗
PubMed1978

Silicone intubation: an alternative to dacryocystorhinostomy.

Silicone intubation is an alternative to dacryocystorhinostomy in selected patients who have epiphora and obstruction of the nasolacrimal system. Silicone tubing may be passed through the nasolacrimal system and left in place for a prolonged period of time. In many instances, this obviates the need for a dacryocystorhinostomy. If the intubation is not completely successful, a dacryocystorhinostomy can always be carried out at a later date.

Dacryocystitis↗
PubMedDate not supplied

The use of scleral transplantation in cicatricial entropion and eyelid retraction.

Scleral transplantation has given excellent results in the surgical repair of eyelid problems. The advantages of using scleral transplantation in repairing eyelid retraction are the relative predictability of the final eyelid position and curve and the decreased incidence of repeated retraction. The characteristics of sclera make it a desirable homologous transplant material for use in transplant surgery.

Entropion↗