PubMed Health⌕ Search

Biomedical subjects

D B Stone

Publications and source records attributed to D B Stone.

At least 37 records · Page 2Linked to original sources
PubMed1976

Knowledge, behavior, and attitudes of sixth-grade students toward family life education.

Although certain exceptions may be noted with respect to sex and type of school, generally lower socioeconomic students obtained lower mean scores on the knowledge and attitude sections of the survey instrument than their counterparts from the higher economic strata. Disadvantaged children from lower socioeconomic levels are reared in an atmosphere hardly conducive to study. Their homes are overcrowded; the children are often hungry, obtain insufficent rest, and possess little interest or motivation for the future--they just live for today. The lower socioeconomic child suffers most when he comes to school. His experiences in living have not prepared him for the demands of the typical school. Shaped by his environment, seeing himself as a person of little worth, he is called upon to conform and communicate. His value system that was bred in deprivation shows sharp contrast to the established "middle class" value system held by the school. Furthermore, disadvantaged children enter school with habits and attitudes that may conflict with many of the traditional modes of teaching. They have had few opportunities to learn the relationship between effort and achievement or to observe that learning has its own reward. Educators have a responsibility to provide the best type of family life education program to meet the needs of all youth. Innovative and challenging ways must be found to make family life education programs relevant to all socioeconomic strata. It would appear essential that educators should possess a thorough knowledge of the economic, social, and cultural conditions that exist in the area in which the educational process is to be conducted.

Attitude↗
PubMed1975

Electron paramagnetic resonance and nanosecond fluorescence depolarization studies on creatine-phosphokinase interaction with myosin and its fragments.

Recent reports in the literature have indicated a physical association of creatine-phosphokinase (CPK) with the tail portion of the myosin molecule. The present paper describes further studies on the interaction of CPK with myosin and myosin fragments, using the techniques of electron paramagnetic resonance (EPR) and nanosecond fluorescence depolarization. From EPR work, spin-labeled CPK appears to interact with myosin, tail-less myosin (heavy meromyosin [HMM]), and myosin heads (subfragment-1 [S1]), the extent of interaction being proportional to the S1 content of myosin or its fragments. Spin-labeled CPK did not evidence interaction with the headless myosin "rods," with myosin tails (light meromyosin [LMM]), with S2 necks (which connect S1 to the rest of the myosin molecule), or with actin. When a fluorescent dye is directed to the essential epsilon-amino group of CPK, nanosecond fluorescence depolarization studies indicate a substantial interaction with myosin, HMM, and S1, but very little with F-actin. When the "fast-reacting" thiol of the S1 moiety or the "essential thiol" of CPK was labeled with either a fluorescent dye or a spin label, no interaction between CPK and myosin (or S1) was detected.

Actins↗