PubMed HealthSearch

Biomedical subjects

D Barov

Publications and source records attributed to D Barov.

11 recordsLinked to original sources

[The plasma amino acid profile of women with a normal pregnancy and in pre-eclampsia].

The authors studied the level of some amino acids in the plasma of 10 women with normal pregnancy as well as of 16 women with moderate form of pre-eclampsia. 21 amino acids were determined by a liquid chromatograph, consisting of an automatic controller of the gradient, nonautomatic injector, fluorimetric detector and recording device. The results showed that there were differences in amino-amides of women with normal pregnancy and of nonpregnant women. Concentrations of a large part of amino acids were not changed, but some of them increased--aspargic acid, glutamate, threonine and phenylalanine or reduced--cytroline, methionine, ornithine, glycine, aspargine, alpha-amino acid during pregnancy. The values of amino-acids in women with normal pregnancy and in women with moderate form of preeclampsia did not differ. Ethanol-amine is the only exception and it is found in almost half of the women with preeclampsia. This is an original finding, which deserves further study.

Adolescent

[Immune responses in women with pre-eclampsia].

Studies were carried out on 26 pregnant women. Sixteen of those women suffered from moderately manifested form of pre-eclampsia, but the remaining ten women had a normal course of pregnancy. The age of women with pre-eclampsia was between 22 to 30 years, but that of the control group--from 30 to 37 years. The women with pre-eclampsia were investigated between 28 to 35 weeks' gestation and the women with normal pregnancy--between 30 to 37 weeks' gestation. Immunoglobulin A, M, G were determined as well as transferrin and T and B lymphocytes. Immunoglobulin A was increased in sera of women with pre-eclampsia, but there were no changes in other examined parameters. It is possible that similar increase could be due to a reduced elimination of immunoglobulin A through the hepatobiliary tract, which cause its elevation in its serum level. The proposed explanation could be accepted as plausible, because there is impairment of liver function in women with preeclampsia. Future studies are needed to prove this fact.

Adolescent

[Changes in specific and nonspecific immune reactivity in women with a complicated obstetrico-gynecologic status].

The immunologic status of some groups of women from the obstetric practice was, studied by using some routine immunologic tests. BT test and C-reactive protein were used in parturients with complicated puerperium. Pregnant women with preserved amniotic sac at tenth lunar month were investigated as well as pregnant women with declared labour activity and ruptured amniotic sac and women with normal pos-partial period and parturients with inflammatory process (complicated puerperium). It was established a statistically significant lowering of active and total T-rosette forming cells and increased level of immunoglobulin G in women with declared labour activity and ruptured amniotic sac. There were lowered values of active T-lymphocytes in parturients with inflammatory complications. The performed studies on these women showed that the usage of BT test and determination of C-reactive protein were indicative methods presenting clear picture of the instant state of the infected organism.

Antibody Formation